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DNA breakthrough could help identify why some people are more affected by Covid-19

COVID-19 MRC MHU RDM

Scientists from the MRC Weatherall Institute of Molecular Medicine have developed a method that allows them to see, with far greater accuracy, how DNA forms large scale structures within a cell nucleus.

New clinical trial for patients affected by blood cancer

MRC MHU RDM

Radcliffe Department of Medicine's Professor Adam Mead is leading PROMise, a new clinical trial offering a novel treatment option for patients with a type of blood cancer called myelofibrosis.

Immune cells imperfect at distinguishing friend from foe

MRC MHU RDM

When it comes to distinguishing a healthy cell from an infected one that needs to be destroyed, the immune system’s killer T cells sometimes make mistakes. This discovery, described today in the journal eLife, upends a long-held belief among scientists that T cells were nearly perfect at discriminating friend from foe. The results may point to new ways to treat autoimmune diseases that cause the immune system to attack the body, or lead to improvements in cutting-edge cancer treatments.

Professor Graham Ogg elected Academy of Medical Sciences Fellow

MRC HIU RDM

Fellows are selected for their exceptional contributions to the advancement of medical science through innovative research discoveries and translating scientific developments into benefits for patients and the wider society.

New funding for early diagnosis research using platelets

MRC MHU RDM

Dr Bethan Psaila and her team will investigate the potential of circulating blood platelets for early detection of a range of cancer types.

Capturing immune cells that colonise the brain to prevent disease progression in multiple sclerosis

NDCN

MRC WIMM researchers have revealed a population of immune cells that travel to the brain in patients with multiple sclerosis causing disease. They demonstrate how to trap these cells in the blood, meaning they can be targeted to prevent disease progression.

New sequencing methods for distinguishing DNA modifications

Expansion of suite of bisulphite-free DNA modification sequencing methods to specifically and directly detect each of the four modifications made to the DNA base cytosine.

MRC WIMM's Noemi Roy among seven projects awarded Public Engagement Seed Funding 2020-21

MRC MHU

Dr Noemi Roy has received funding in the 2020-21 round of the Public Engagement with Research Seed Fund as one of seven projects for innovative work to engage the public with medical research.

New study maps the development of the human intestine

MRC HIU RDM

Researchers in the Simmons lab chart the embryonic origins and appearance of diverse intestinal cellular compartments, with important implications for intestinal diseases.

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