MRC Molecular Haematology Unit
We aim to understand how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders. Ultimately, our purpose is to improve the prognosis of patients with inherited and acquired blood diseases.
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus.
Oudelaar AM. et al, (2019), Nat Commun, 10
Single cell analysis of bone marrow derived CD34+ cells from children with sickle cell disease and thalassemia.
Hua P. et al, (2019), Blood
Ochs F. et al, (2019), Nature, 574, 571 - 574