MRC Molecular Haematology Unit
At the MRC Molecular Haematology Unit, we aim to understand how stem cells produce mature blood cells in a healthy context, and how this process is perturbed in common blood disorders.
MRC MHU includes 14 research teams with over 140 scientists who share a common goal, to improve the prognosis of patients with inherited and acquired blood diseases.
This is an exciting time for the field of haematology. The -omics revolution is enabling scientists to unravel the complex molecular processes governing biology at unprecedented speed. At the MRC MHU our teams are committed to applying such cutting-edge techniques to better understand the molecular basis of blood diseases, and to develop treatments to improve the lives of patients. - Professor KJ Patel
Latest publications
The Thrombopoietin Receptor S264F Mutant Drives MPN with Marrow Fibrosis Through a Dual Mechanism
Journal article
MEAD A., (2026), HemaSphere
Nucleophagy as an emerging therapeutic vulnerability in cancer.
Journal article
Tribble S. and Ramadan K., (2026), Autophagy, 1 - 3
The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome.
Journal article
Boucher AC. et al, (2026), Leukemia
Identification of a novel deeply quiescent neural stem cell population in the subventricular zone: a potential source for brain repair.
Journal article
Nath AR. et al, (2026), Cell Discov, 12
The challenge and promise of studying human antigen-specific T cells.
Journal article
Farrar S. et al, (2026), Nat Rev Immunol