MRC Molecular Haematology Unit
New technology helps decode the genetic changes behind disease
Researchers from the Milne, Hughes and Davies Groups have developed a new technology that can reveal new therapeutic targets from common genetic variants linked to disease.
Read moreEveryday DNA damage reveals a hidden weakness in some cancers
Researchers in the Chapman Group have discovered why cancer cells lacking a protein called ATM are particularly vulnerable to a class of cancer drugs known as PARP inhibitors, solving a scientific puzzle that has challenged researchers for nearly 20 years.
Read moreProfessor Marella de Bruijn receives MRC Programme Award
Congratulations to Professor de Bruijn, who has been awarded funding from the UKRI Medical Research Council to investigate how the first blood stem cells formed in the embryo acquire their exceptional regenerative potential, with the aim of informing future stem cell therapies.
Read moreProfessor KJ Patel awarded Royal Society Buchanan Medal
Congratulations to Professor Patel, who has received the Buchanan Medal, which recognises distinguished contributions to the biomedical sciences.
Read moreProfessor Bethan Psaila wins ISEH Janet Rowley Award
Congratulations to Professor Psaila, who has received the 2026 Janet Rowley Award from the International Society for Experimental Hematology, in recognition of her outstanding contributions in the field of experimental haematology.
Read moreAt the MRC Molecular Haematology Unit, we aim to understand how stem cells produce mature blood cells in a healthy context, and how this process is perturbed in common blood disorders.
MRC MHU includes 14 research teams with over 140 scientists who share a common goal, to improve the prognosis of patients with inherited and acquired blood diseases.
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This is an exciting time for the field of haematology. The -omics revolution is enabling scientists to unravel the complex molecular processes governing biology at unprecedented speed. At the MRC MHU our teams are committed to applying such cutting-edge techniques to better understand the molecular basis of blood diseases, and to develop treatments to improve the lives of patients. - Professor KJ Patel
MRC MHU Director- Professor KJ Patel
Latest publications
Paediatric traumatic brain injury: clinical presentation, treatment approaches, management strategies, and outcomes. Insights from the CENTER-TBI study
Journal article
Graziano F. et al, (2026), Journal of Anesthesia Analgesia and Critical Care, 6
Can It Happen Again? Using Co-Produced Theatre to Explore the Challenges Faced by Couples Considering Pregnancy After a De Novo Genetic Diagnosis in a Child.
Journal article
Kay A. et al, (2026), Health Expect, 29
Coronary Inflammation Is Associated With Plaque Progression in Men With HIV.
Journal article
Nasrallah N. et al, (2026), Circ Cardiovasc Imaging
Recombinant shingles vaccination and the risk of cardiovascular events.
Journal article
Corsi-Zuelli F. et al, (2026), Nat Med