MRC Molecular Haematology Unit
At the MRC Molecular Haematology Unit, we aim to understand how stem cells produce mature blood cells in a healthy context, and how this process is perturbed in common blood disorders.
MRC MHU includes 14 research teams with over 140 scientists who share a common goal, to improve the prognosis of patients with inherited and acquired blood diseases.
This is an exciting time for the field of haematology. The -omics revolution is enabling scientists to unravel the complex molecular processes governing biology at unprecedented speed. At the MRC MHU our teams are committed to applying such cutting-edge techniques to better understand the molecular basis of blood diseases, and to develop treatments to improve the lives of patients. - Professor KJ Patel
Latest publications
Zone Equalisation Normalisation for Improved Alignment of Epigenetic Signal.
Journal article
Wilson T. et al, (2026), Bioinformatics
Identification and Masking of Artefactual and Misleading Within-Host Variants in Deep-Sequencing SARS-CoV-2 Data.
Journal article
Anker KM. et al, (2026), Mol Biol Evol
Identifying phenotype-genotype-function coupling in 3D organoid imaging using Shape, Appearance and Motion Phenotype Observation Tool (SPOT).
Journal article
Zhou FY. et al, (2026), Nat Commun, 17
Loss of cellular RNA homeostasis contributes to MDA5 activation during virus infection.
Journal article
Sampaio NG. et al, (2026), Nat Immunol
Transmission ratio distortion of NF1 mutant alleles in familial Neurofibromatosis type 1.
Journal article
Pei Y. et al, (2026), Genet Med