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‘Targeted Therapies’ at Big Bang Fair 2025

Earlier this year, a group of researchers from the MRC Weatherall Institute of Molecular Medicine attended the Big Bang Fair in Birmingham, showcasing medical research through a series of hands-on activities.

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Leading research with the aim of improving human health.

© Photo by Kzenon

Translating Our Research

Leading research with the aim of improving human health. World-leading research from scientists at the MRC WIMM has been developed into commercial ventures to translate our discoveries into clinics and benefit patients.

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Microsopy image showing DNA inside platelets.

© Lauren Murphy

Platelets Shown to Store DNA in Study that could Transform Cancer Screening

Study led by Psaila Group uncovers previously unknown function of platelets as DNA ‘vacuum cleaners’ in the blood, with profound implications for cancer diagnosis and prenatal screening.

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The MRC WIMM's core mission is to improve human health through the pursuit of fundamental research, the development of new technology, and the translation of discoveries to the clinic.

Discover. Translate. Advance.

The MRC WIMM's core mission is to improve human health through the pursuit of fundamental research, the development of new technology, and the translation of discoveries to the clinic.

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AI-generated 3D Illustration showing human lung alveoli

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Researchers create first atlas showing cell interactions in lung fibrosis

New study uncovers key immune cell interaction that could explain failed lung repair in idiopathic pulmonary fibrosis (IPF)

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Research at the MRC WIMM spans 5 core areas.

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MRC WIMM Research Areas

Research at the MRC WIMM spans 5 core areas.

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MRC Translational Immune Discovery Unit

Pioneering the future in the study of human immunity to uncover the molecular pathways driving immune-mediated diseases.

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MRC Molecular Haematology Unit

Understanding how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders.

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Centre for Computational Biology

Using computational biology to help understand complex biological systems and combat a range of human diseases.

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Latest publications

RAB23 loss-of-function mutation causes context-dependent ciliopathy in Carpenter syndrome.
Journal article

Leong WY. et al, (2025), PLoS Genet, 21
Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA.
Journal article

Murphy L. et al, (2025), Science, 389
Charting New Paths in Cancer Research: Insights from the Frontiers in Cancer Science Conference 2024.
Journal article

Le Minh G. et al, (2025), Cancer Res, 85, 2784 - 2787

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Upcoming Seminars

Proteolysis-mediated regulation of red blood cell maturation

Tuesday, 02 September 2025, 1pm to 2pm

Speakers: Dr Arno Alpi
Targeting KRAS oncogenic signalling and tumour immune evasion in lung cancer

Thursday, 04 September 2025, 12pm to 1pm

Speakers: Professor Julian Downward
Title TBC

Tuesday, 16 September 2025, 1pm to 2pm
No Drama, Just Llama: Trading Small Molecules for Big Antibodies”

Monday, 29 September 2025, 12pm to 1pm

Speakers: Christel Menet, PhD

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MRC WIMM Interactive Timeline

Accessible Version of Timeline