News — MRC Weatherall Institute of Molecular Medicine

Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

3 April 2024

New research published in Nature Immunology showcases the collaborative efforts of MRC TIDU researchers to describe a novel pairing of integrins which could improve T cell control of cancer.

An illustration showing the surfaces of two cells coming together, with one at the top of the image and one at the bottom. A purple molecule protruding downwards from the top 'cell' and a green molecule protruding upwards from the bottom 'cell' are both bound to the same yellow molecule in the middle of the image. A red molecule protrudes downwards from the surface of the bottom cell. There is a large blue molecule to the right of the image that can't 'fit' between the two 'cells' where the interaction with the yellow molecule is occurring.

New study provides framework for optimising the design of antibody therapeutics

13 February 2024

Representation of a DNA helix with different coloured lights dotted throughout.

Researchers define new class of regulatory element in DNA

14 December 2023

MRC TIDU Spotlight Series: Dong Group

29 November 2023

In the sixth instalment of the MRC TIDU Spotlight Series, we're taking a look at Tao Dong's Group.

Illustration of antibodies attacking SARS-CoV-2 virus

New details uncovered about the process of antibody production during immune response

10 November 2023

Visual illustration of inside of lungs infected with COVID.

Single cell spatial analysis provides new insight into immune-pathology in Covid-19 lungs

9 November 2023

Close-up image of a man and a woman in a lab.

MRC TIDU Spotlight Series: Ho Group

27 October 2023

In the next instalment of the MRC TIDU Spotlight Series, we are focusing on the Ho Group.

Tao Dong appointed the Brigitte (Ita) Askonas Professor of Translational Immunology

20 July 2023

With effect from 1st May 2023, Professor Tao Dong, has been appointed the Brigitte (Ita) Askonas Professor of Translational Immunology.

Microscopy image showing green spots that are tingle body macrophages, with holes that are vacuoles full of apoptotic debris.

Study maps origin of macrophage population important for cellular ‘clear up’ in the immune system

22 March 2023

New UK research consortium formed to tackle monkeypox outbreak

24 October 2022

Investigation of the T cell responses against monkeypox virus will be led by Prof. Tao Dong at the CAMS-Oxford Institute and MRC Human Immunology Unit.

Ziqi Long receives NDM Prize

3 October 2022

DPhil student Ziqi Long has been commended in the category NDM Overall Prize at the annual Nuffield Department of Medicine (NDM) Awards

Learn about cutting-edge research at Oxford Open Doors 2022

5 September 2022

On Saturday 10th September 2022 12.30-4 pm, the MRC WIMM will be joining colleagues from the Medical Sciences Division at the Old Road Campus Research Building (ORCRB) as part of the Oxford Open Doors programme. This event is open to everyone.

Fundraising for award in memory of Dr Ling Felce

1 September 2022

The Ling Felce award will promote cross-disciplinary excellence in bioinformatics.

Study of T-cell receptor activation leads to surprising discovery

18 August 2022

A study from Davis Group is the first to describe the structure of the T-cell receptor when bound to an activating ligand. The findings shed light on an important trigger in the immune system, and suggest a completely new process by which cell receptors can be activated.

Confocal microscopy of a lung section, 4 days after being rechallenged with an influenza virus. Resident memory B cells (red) and newly generated plasma cells (yellow) can be seen in very close proximity to infected cells (light blue).

Defining the role of resident memory B cells in the fight against influenza

31 March 2022

Researchers at the Kennedy Institute of Rheumatology and the MRC Human Immunology Unit have used 3D and live-imaging to show how resident memory B cells boost antibodies to fight influenza.

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