MRC Human Immunology Unit
At the MRC Human Immunology Unit we propel the understanding and treatment of immune mediated diseases.
MRC HIU includes 16 research teams with over 160 scientists who share a common goal - to harness the immune system to enhance human health.
Collaboration and innovation lie at the heart of the MRC HIU. Our research groups work together to understand how the human immune system functions, what happens when it fails, and how we can use our knowledge of these systems to improve patient outcomes. By working together with clinicians, industry and charities, we aim to translate our scientific findings at the HIU so that they can have a positive impact on global health. - Professor Alison Simmons
MRC MHU Director- Professor Alison Simmons
Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites.
MacLean AJ. et al, (2022), Immunity
Competition for refueling rather than cyclic reentry initiation evident in germinal centers.
Long Z. et al, (2022), Sci Immunol, 7
SARS-CoV-2 peptides bind to NKG2D and increase NK cell activity.
Kim H. et al, (2021), Cell Immunol, 371
BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration
LEEDHAM S. et al, (2021), Gastroenterology