MRC Molecular Haematology Unit
Professor KJ Patel awarded major European Research Council Advanced Grant
Professor Patel is one of fourteen researchers at the University of Oxford awarded Advanced Grants from the European Research Council (ERC), each worth up to €2.5 million over a period of five years.
Read moreAt the MRC Molecular Haematology Unit, we aim to understand how stem cells produce mature blood cells in a healthy context, and how this process is perturbed in common blood disorders.
MRC MHU includes 14 research teams with over 140 scientists who share a common goal, to improve the prognosis of patients with inherited and acquired blood diseases.
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Public Engagement
This is an exciting time for the field of haematology. The -omics revolution is enabling scientists to unravel the complex molecular processes governing biology at unprecedented speed. At the MRC MHU our teams are committed to applying such cutting-edge techniques to better understand the molecular basis of blood diseases, and to develop treatments to improve the lives of patients. - Professor KJ Patel
MRC MHU Director- Professor KJ Patel
Latest publications
Gut microbiota restricts intestinal lipid uptake via modulation of bile phosphatidylcholine metabolism in mice.
Journal article
Brunner S. et al, (2026), Nat Microbiol, 11, 2349 - 2364
The Thrombopoietin Receptor S264F Mutant Drives MPN with Marrow Fibrosis Through a Dual Mechanism
Journal article
MEAD A., (2026), HemaSphere
Resolving hematopoietic stem versus progenitor cell potential in the mouse dorsal aorta by differential Runx1 +110 enhancer activity.
Journal article
Anselmi G. et al, (2026), Cell Rep, 45
Nucleophagy as an emerging therapeutic vulnerability in cancer.
Journal article
Tribble S. and Ramadan K., (2026), Autophagy, 1 - 3
The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome.
Journal article
Boucher AC. et al, (2026), Leukemia