Wolfson Imaging Centre
The Wolfson Imaging Centre is an open access light microscopy core facility. Our facility includes a wide range of state-of-the-art widefield and confocal light microscopes suitable for imaging a variety of specimens.
Visit our intranet page for more details on our equipment, pricing and SOPs.
The Wolfson Imaging Facility houses a variety of state-of-the art widefield and confocal microscopes, accessible to both internal and external users. Uniquely, the Facility houses the only commercial STED microscope open to users at the University of Oxford, offering advanced, super-resolution imaging solutions for cutting-edge research projects.
The Facility staff provides training to allow independent use of the equipment, but is also available for advice regarding experiment design, data acquisition and analysis.
We actively collaborate and share resources with the Micron Advanced Bioimaging Unit at the Department of Biochemistry and the Sir William Dunn School for Pathology. The Facility staff further interacts regularly with other similar facilities at the CRUK/MRC Oxford Institute for Radiation Oncology, the Kennedy Institute, the Wellcome Centre for Human Genetics and more.
The Lateral Organization and Mobility of Plasma Membrane Components.
Jacobson K. et al, (2019), Cell. 177(4): 806-819
An essential role for the Zn2+ transporter ZIP7 in B cell development.
Anzilotti C, et al, (2019), Nature Immunology. 20(3):350-361
Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.
Sezgin E, et al, (2019), Nature Protocols. 14(4):1054-1083
Colonic epithelial cell diversity in health and inflammatory bowel disease.
Parikh K, et al, (2019), Nature. 567, 49–55
From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo.
Lukoseviciute M, et al, (2018), Dev Cell. 47(5):608-628
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.
Brown JM, et al, (2018), Nature Communications. 9(1), 3849
Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells.
Neo WH, et al, (2018), Blood. 131(20), 2223-2234
Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Zheng Y, et al, (2018), Nature communications. 9(1), 476
The Wolfson Imaging Centre was established in late 2012 with funding from the Wolfson Foundation, and since then we have benefitted from further funding.