Publications

Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation.

Chen Y-L. et al, (2023), Sci Immunol, 8

Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.

Monnot GC. et al, (2022), Nat Immunol

CD1a promotes systemic manifestations of skin inflammation.

Hardman CS. et al, (2022), Nat Commun, 13

Dengue virus co-opts innate type 2 pathways to escape early control of viral replication.

Fonseka CL. et al, (2022), Commun Biol, 5

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58

Phospholipase activity of acyloxyacyl hydrolase induces IL-22-producing CD1a-autoreactive T cells in individuals with psoriasis.

Singh R. et al, (2022), Eur J Immunol, 52, 511 - 524

Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19.

Frost JN. et al, (2022), Wellcome open research, 7

Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19.

Frost JN. et al, (2022)

Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients.

Youngs J. et al, (2021), PLoS Pathog, 17

Pre-existing asthma as a comorbidity does not modify cytokine responses and severity of COVID-19.

Luo J. et al, (2021), Allergy Asthma Clin Immunol, 17

CD1a selectively captures endogenous cellular lipids that broadly block T cell response.

Cotton RN. et al, (2021), J Exp Med, 218

IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent.

Hardman CS. et al, (2021), Sci Immunol, 6

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None. et al, (2021)

Role of regulatory T cells in psoriasis pathogenesis and treatment.

Nussbaum L. et al, (2021), Br J Dermatol, 184, 14 - 24

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.

Peng Y. et al, (2020), Nat Immunol, 21, 1336 - 1345

Innate Lymphocyte Mechanisms in Skin Diseases.

Chen Y-L. et al, (2020), 38, 171 - 202

Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation.

Chen Y-L. et al, (2020), J Exp Med, 217

Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells.

Luo J. et al, (2019), J Allergy Clin Immunol, 144, 1722 - 1726.e10

Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis.

Chen Y-L. et al, (2019), Sci Transl Med, 11

Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function.

Hardman C. et al, (2019), J Allergy Clin Immunol, 143, 2329 - 2333

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Publications