Recent publications published by researchers at the MRC WIMM.
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
Journal article
Hamid MHBA. et al, (2024), Nat Immunol
A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells.
Journal article
Sharma S. et al, (2024), Life Sci Alliance, 7
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation.
Journal article
Chen Y-L. et al, (2023), Sci Immunol, 8
Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.
Journal article
Monnot GC. et al, (2022), Nat Immunol
CD1a promotes systemic manifestations of skin inflammation.
Journal article
Hardman CS. et al, (2022), Nat Commun, 13
Dengue virus co-opts innate type 2 pathways to escape early control of viral replication.
Journal article
Fonseka CL. et al, (2022), Commun Biol, 5
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
Journal article
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58
Phospholipase activity of acyloxyacyl hydrolase induces IL-22-producing CD1a-autoreactive T cells in individuals with psoriasis.
Journal article
Singh R. et al, (2022), Eur J Immunol, 52, 511 - 524
Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19.
Journal article
Frost JN. et al, (2022), Wellcome open research, 7
Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19.
Preprint
Frost JN. et al, (2022)
Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients.
Journal article
Youngs J. et al, (2021), PLoS Pathog, 17
Pre-existing asthma as a comorbidity does not modify cytokine responses and severity of COVID-19.
Journal article
Luo J. et al, (2021), Allergy Asthma Clin Immunol, 17
CD1a selectively captures endogenous cellular lipids that broadly block T cell response.
Journal article
Cotton RN. et al, (2021), J Exp Med, 218
IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent.
Journal article
Hardman CS. et al, (2021), Sci Immunol, 6
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
Working paper
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None. et al, (2021)
Role of regulatory T cells in psoriasis pathogenesis and treatment.
Journal article
Nussbaum L. et al, (2021), Br J Dermatol, 184, 14 - 24
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.
Journal article
Peng Y. et al, (2020), Nat Immunol, 21, 1336 - 1345
Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation.
Journal article
Chen Y-L. et al, (2020), J Exp Med, 217
Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells.
Journal article
Luo J. et al, (2019), J Allergy Clin Immunol, 144, 1722 - 1726.e10