Recent publications published by researchers at the MRC WIMM.
Reassessing the association: evaluation of a polyalanine deletion variant of RUNX2 in non-syndromic sagittal and metopic craniosynostosis
Journal article
Walton I. et al, (2024), Journal of Anatomy
Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors.
Journal article
Suchy FP. et al, (2024), Nat Biotechnol
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia.
Journal article
Milne TA., (2024), Curr Opin Genet Dev, 86
The road to refractory graft-versus-host disease is paved with good intentions
Journal article
North D. and Chakraverty R., (2024), Journal of Clinical Investigation, 134
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
Journal article
Hamid MHBA. et al, (2024), Nat Immunol
Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.
Journal article
Xiang G. et al, (2024), bioRxiv
Aberrant stem cell and developmental programs in pediatric leukemia
Journal article
Ling RE. et al, (2024), Frontiers in Cell and Developmental Biology, 12
Generating human bone marrow organoids for disease modeling and drug discovery.
Journal article
Olijnik A-A. et al, (2024), Nat Protoc
Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid resistance.
Journal article
Michl J. et al, (2024), Proc Natl Acad Sci U S A, 121
Homozygous SMAD6 variants in two unrelated patients with craniosynostosis and radioulnar synostosis.
Journal article
Luyckx I. et al, (2024), J Med Genet, 61, 363 - 368
Speech and Language Development, Hearing, and Feeding in Patients With Genetically Confirmed Crouzon Syndrome With Acanthosis Nigricans: A 36-Year Longitudinal Retrospective Review of Patients at the Oxford Craniofacial Unit.
Journal article
Kilcoyne S. et al, (2024), J Craniofac Surg
Human spermatogonial stem cells retain states with a foetal-like signature
Preprint
Bush SJ. et al, (2024)
Unraveling the molecular interactions between α7 nicotinic receptor and a RIC3 variant associated with backward speech.
Journal article
Pradhan A. et al, (2024), Cell Mol Life Sci, 81
Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future.
Journal article
Amid A. et al, (2024), Blood
Take the MYC to expand blood stem cells.
Journal article
Wilkinson AC., (2024), Blood, 143, 838 - 840
A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells.
Journal article
Sharma S. et al, (2024), Life Sci Alliance, 7
A repair pathway lost in multiple sclerosis provides a new drug opportunity.
Journal article
Jensen LT. et al, (2024), Nat Immunol, 25, 385 - 386
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19.
Journal article
Hanson AL. et al, (2024), Nat Immunol, 25, 471 - 482
Novel role of bone morphogenetic protein 9 in innate host responses to HCMV infection.
Journal article
Stempel M. et al, (2024), EMBO Rep, 25, 1106 - 1129
Research Protocol : Putting the Person in the PICTuRE - Personalised Informed Consent in TissUe donation for Research lived Experiences
Poster
Mawhinney G. et al, (2024)