Recent publications published by researchers at the MRC WIMM.
Silencing of SOD1 sensitises ATRX-deficient cells to camptothecin treatment through increased activity of the Alternative Lengthening of Telomeres pathway
ROSE A. et al, (2025), Human Molecular Genetics
Elevated reactive oxygen species can drive the alternative lengthening of telomeres pathway in ATRX-null cancers.
Goncalves T. et al, (2025), Nucleic Acids Res, 53
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length.
Kliszczak M. et al, (2023), Front Cell Dev Biol, 11