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Publications

Recent publications published by researchers at the MRC WIMM.

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

Journal article

Lippert AH. et al, (2024), Immunity, 57, 256 - 270.e10

Single-cell measurements of two-dimensional binding affinity across cell contacts.

Conference paper

Chouliara M. et al, (2021), Biophys J, 120, 5032 - 5040

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling.

Journal article

Chen KY. et al, (2021), Proc Natl Acad Sci U S A, 118

The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale.

Journal article

Kulenkampff K. et al, (2020), Biophys J, 118, 1261 - 1269

A cell topography-based mechanism for ligand discrimination by the T cell receptor.

Journal article

Fernandes RA. et al, (2019), Proc Natl Acad Sci U S A, 116, 14002 - 14010

Constraints on GPCR Heterodimerization Revealed by the Type-4 Induced-Association BRET Assay.

Journal article

Felce JH. et al, (2019), Biophys J, 116, 31 - 41

Inside-out mechanisms of CD6 signaling: cytoplasmic and extracellular interactions impact on T cell activation

Conference paper

Santos RF. et al, (2019), EUROPEAN JOURNAL OF IMMUNOLOGY, 49, 346 - 347

Investigation into how T cells trigger on various surfaces

Conference paper

Dam T. et al, (2019), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 48, S190 - S190

Measuring GPCR Stoichiometry Using Types-1, -2, and -3 Bioluminescence Resonance Energy Transfer-Based Assays.

Journal article

Felce JH. et al, (2019), Methods Mol Biol, 1947, 183 - 197

Single cell measurements of protein affinity in contacting cells

Conference paper

Chouliara M. et al, (2019), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 48, S190 - S190

The Interplay of Immune Cell Proteins Affects the Orientation, Organisation and Affinity within a Cell -Cell

Conference paper

Junghans V. et al, (2019), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 48, S191 - S191

CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.

Journal article

Felce JH. et al, (2018), Sci Signal, 11

LAG-3: a very singular immune checkpoint.

Journal article

Lui Y. and Davis SJ., (2018), Nat Immunol, 19, 1278 - 1279

Reconstitution of immune cell interactions in free-standing membranes.

Journal article

Jenkins E. et al, (2018), J Cell Sci, 132

Hydrodynamic trapping measures the interaction between membrane-associated molecules.

Journal article

Junghans V. et al, (2018), Sci Rep, 8

Single-Molecule Light-Sheet Imaging of Suspended T Cells.

Journal article

Ponjavic A. et al, (2018), Biophys J, 114, 2200 - 2211

Monomeric TCRs drive T cell antigen recognition.

Journal article

Brameshuber M. et al, (2018), Nat Immunol, 19, 487 - 496

Capturing resting T cells: the perils of PLL.

Journal article

Santos AM. et al, (2018), Nat Immunol, 19, 203 - 205

Single-Molecule Analysis of G Protein-Coupled Receptor Stoichiometry: Approaches and Limitations.

Journal article

Felce JH. et al, (2018), Trends Pharmacol Sci, 39, 96 - 108

Dimensions and Interactions of Large T-Cell Surface Proteins.

Journal article

Junghans V. et al, (2018), Front Immunol, 9

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