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Publications

Recent publications published by researchers at the MRC WIMM.

Epigenetic programming defines haematopoietic stem cell fate restriction.

Meng Y. et al, (2023), Nat Cell Biol, 25, 812 - 822

Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.

Braun TP. et al, (2022), Nat Commun, 13

Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing.

Valletta S. et al, (2020), Nat Commun, 11

C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.

Di Genua C. et al, (2020), Cancer Cell, 37, 690 - 704.e8

Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.

Braun TP. et al, (2019), Nat Commun, 10

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.

Di Genua C. et al, (2019), Haematologica, 104, 2215 - 2224

Identification of two distinct pathways of human myelopoiesis.

Drissen R. et al, (2019), Sci Immunol, 4

Studying BDNF/TrkB Signaling: High-Throughput Microfluidic Gene Expression Analysis from Rare or Limited Samples of Adult and Aged Central Neurons

Nath AR. et al, (2019), Neuromethods, 143, 77 - 86

Hematopoietic Lineage Diversification, Simplified.

Drissen R. and Nerlov C., (2016), Cell Stem Cell, 19, 148 - 150

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Drissen R. et al, (2016), Nat Immunol, 17, 666 - 676

DISTINCT MYELOID PROGENITOR DIFFERENTIATION PATHWAYS IDENTIFIED THROUGH SINGLE CELL RNA SEQUENCING

Nerlov C. et al, (2016), EXPERIMENTAL HEMATOLOGY, 44, S46 - S46

Lineage-specific combinatorial action of enhancers regulates mouse erythroid Gata1 expression.

Drissen R. et al, (2010), Blood, 115, 3463 - 3471

Transcriptional regulation of GATA1

Drissen R. et al, (2007), BLOOD CELLS MOLECULES AND DISEASES, 38, 186 - 187

A hanging drop culture method to study terminal erythroid differentiation

Gutiérrez L. et al, (2005), Experimental Hematology, 33, 1083 - 1091

The Erythroid Phenotype of EKLF-Null Mice: Defects in Hemoglobin Metabolism and Membrane Stability

Drissen R. et al, (2005), Molecular and Cellular Biology, 25, 5205 - 5214

The active spatial organization of the -globin locus requires the transcription factor EKLF

Drissen R., (2004), Genes & Development, 18, 2485 - 2490

Identification of a Peroxisomal ATP Carrier Required for Medium-Chain Fatty Acid β-Oxidation and Normal Peroxisome Proliferation in Saccharomyces cerevisiae

van Roermund CWT. et al, (2001), Molecular and Cellular Biology, 21, 4321 - 4329

B-cell-autonomous somatic mutation deficit following bone marrow transplant.

Glas AM. et al, (2000), Blood, 96, 1064 - 1069

Include forthcoming?