Recent publications published by researchers at the MRC WIMM.
Unraveling the molecular interactions between α7 nicotinic receptor and a RIC3 variant associated with backward speech.
Pradhan A. et al, (2024), Cell Mol Life Sci, 81
IgG1-3 MuSK Antibodies Inhibit AChR Cluster Formation, Restored by SHP2 Inhibitor, Despite Normal MuSK, DOK7, or AChR Subunit Phosphorylation.
Cao M. et al, (2023), Neurol Neuroimmunol Neuroinflamm, 10
NSC-87877, INHIBITOR OF SRC HOMOLOGY 2 DOMAIN-CONTAINING PHOSPHOTYROSINE PHOSPHATASE 2, AMELIORATES EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS INDUCED BY MUSK IMMUNIZATION
Yilmaz V. et al, (2022), MUSCLE & NERVE, 65, S45 - S45
The Structure, Function, and Physiology of the Fetal and Adult Acetylcholine Receptor in Muscle.
Cetin H. et al, (2020), Front Mol Neurosci, 13
Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation.
Oprişoreanu A-M. et al, (2019), Cell Rep, 29, 1082 - 1098.e10
Animal Models of the Neuromuscular Junction, Vitally Informative for Understanding Function and the Molecular Mechanisms of Congenital Myasthenic Syndromes.
Webster RG., (2018), Int J Mol Sci, 19
Serological and experimental studies in different forms of myasthenia gravis.
Vincent A. et al, (2018), Ann N Y Acad Sci, 1413, 143 - 153
Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient.
Saxena A. et al, (2017), Sci Rep, 7
Multiple roles of integrin-α3 at the neuromuscular junction.
Ross JA. et al, (2017), J Cell Sci, 130, 1772 - 1784
Fast-channel congenital myasthenic syndrome with a novel acetylcholine receptor mutation at the α-ε subunit interface
Webster R. et al, (2014), Neuromuscular Disorders, 24, 143 - 147
A mouse model of the slow channel myasthenic syndrome: Neuromuscular physiology and effects of ephedrine treatment.
Webster RG. et al, (2013), Exp Neurol, 248, 286 - 298
Mutations in GFPT1 that underlie limb-girdle congenital myasthenic syndrome result in reduced cell-surface expression of muscle AChR.
Zoltowska K. et al, (2013), Hum Mol Genet, 22, 2905 - 2913
Slow channel congenital myasthenic syndrome responsive to a combination of fluoxetine and salbutamol.
Finlayson S. et al, (2013), Muscle Nerve, 47, 279 - 282
FAST CHANNEL CONGENITAL MYASTHENIA: REVIEW OF 12 CASES AND TREATMENT CHALLENGES
Finlayson S. et al, (2012), JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83, A23 - A23
Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis.
Jacob S. et al, (2012), Arch Neurol, 69, 994 - 1001
A novel congenital myasthenic syndrome due to decreased acetylcholine receptor ion-channel conductance.
Webster R. et al, (2012), Brain, 135, 1070 - 1080
Passive and active immunization models of MuSK-Ab positive myasthenia: electrophysiological evidence for pre and postsynaptic defects.
Viegas S. et al, (2012), Exp Neurol, 234, 506 - 512
A novel congenital myasthenic syndrome due to decreased acetylcholine receptor ion-channel conductance
Webster R. et al, (2012), Brain, 135, 1070 - 1080
Fluorescent receptors to light up the neuromuscular junction
Cossins J. et al, (2011), NEUROMUSCULAR DISORDERS, 21, S12 - S13
Impaired neurotransmission in a mouse model of the slow channel congenital myasthenic syndrome is improved by the sympathomimetic drug ephedrine
Webster R. et al, (2011), NEUROMUSCULAR DISORDERS, 21, S15 - S15