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Publications

Recent publications published by researchers at the MRC WIMM.

RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death.

Schilling M. et al, (2020), Cells, 9

Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation.

Chen Y-L. et al, (2020), J Exp Med, 217

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.

Di Genua C. et al, (2019), Haematologica, 104, 2215 - 2224

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.

Gooding S. et al, (2019), Nat Commun, 10

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.

Morotti M. et al, (2019), Proc Natl Acad Sci U S A, 116, 12452 - 12461

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.

Chagraoui H. et al, (2018), Nat Commun, 9

Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.

Aleksic T. et al, (2018), Cancer Res, 78, 3497 - 3509

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.

Duarte S. et al, (2018), Blood, 131, 1712 - 1719

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Pasricha S-R. et al, (2017), Nat Commun, 8

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

Mead AJ. et al, (2017), J Exp Med, 214, 2005 - 2021

Intragenic enhancers act as alternative promoters.

Kowalczyk MS. et al, (2012), Mol Cell, 45, 447 - 458

Global gene expression analysis of human erythroid progenitors.

Merryweather-Clarke AT. et al, (2011), Blood, 117, e96 - 108

The role of the polycomb complex in silencing alpha-globin gene expression in nonerythroid cells.

Garrick D. et al, (2008), Blood, 112, 3889 - 3899

Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

Brown JM. et al, (2008), J Cell Biol, 182, 1083 - 1097

The expression profile for the tumour suppressor gene PTEN and associated polymorphic markers.

Hamilton JA. et al, (2000), Br J Cancer, 82, 1671 - 1676

Include forthcoming?