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Recent publications published by researchers at the MRC WIMM.

Ancient DNA reveals evolutionary origins of autoimmune diseases.

Journal article

Barrie W. et al, (2024), Nat Rev Immunol

Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations.

Journal article

Barrie W. et al, (2024), Nature, 625, 321 - 328

The selection landscape and genetic legacy of ancient Eurasians.

Journal article

Irving-Pease EK. et al, (2024), Nature, 625, 312 - 320

Allosteric TYK2 inhibition: redefining autoimmune disease therapy beyond JAK1-3 inhibitors.

Journal article

Jensen LT. et al, (2023), EBioMedicine, 97

Identification of early neurodegenerative pathways in progressive multiple sclerosis.

Journal article

Kaufmann M. et al, (2022), Nat Neurosci

The immunology of multiple sclerosis.

Journal article

Attfield KE. et al, (2022), Nat Rev Immunol

MOG antibody-associated disease after vaccination with ChAdOx1 nCoV-19.

Journal article

Francis A. et al, (2022), Lancet Neurol, 21, 217 - 218

Inflammation-related plasma and CSF biomarkers for multiple sclerosis.

Journal article

Huang J. et al, (2020), Proc Natl Acad Sci U S A, 117, 12952 - 12960

A novel neurodegenerative spectrum disorder in patients with MLKL deficiency.

Journal article

Faergeman SL. et al, (2020), Cell Death Dis, 11

Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.

Journal article

Cortes A. et al, (2020), Nat Genet, 52, 126 - 134

HLA variation and disease.

Journal article

Dendrou CA. et al, (2018), Nat Rev Immunol, 18, 325 - 339

The Human Cell Atlas.

Journal article

Regev A. et al, (2017), Elife, 6

Immunomodulation in multiple sclerosis: promises and pitfalls.

Journal article

Dendrou CA. and Fugger L., (2017), Curr Opin Immunol, 49, 37 - 43

Structural and regulatory diversity shape HLA-C protein expression levels.

Journal article

Kaur G. et al, (2017), Nat Commun, 8

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