Recent publications published by researchers at the MRC WIMM.
Spatiotemporal analysis of human intestinal development at single-cell resolution.
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Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23
Single-cell atlas of colonic CD8+ T cells in ulcerative colitis.
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Corridoni D. et al, (2020), Nat Med, 26, 1480 - 1490
Colonic epithelial cell diversity in health and inflammatory bowel disease.
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Parikh K. et al, (2019), Nature, 567, 49 - 55
Glyco-conjugated bile acids drive the initial metaplastic gland formation from multi-layered glands through crypt-fission in a murine model.
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Straub D. et al, (2019), PLoS One, 14
Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.
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Kinchen J. et al, (2018), Cell, 175, 372 - 386.e17
Microbiome, pattern recognition receptor function in health and inflammation.
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Fawkner-Corbett D. et al, (2017), Best Pract Res Clin Gastroenterol, 31, 683 - 691
Modulation of Human Peripheral Blood Mononuclear Cell Signaling by Medicinal Cannabinoids
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Utomo WK. et al, (2017), Frontiers in Molecular Neuroscience, 10
Increased phosphorylation on residue S795 of the retinoblastoma protein in esophageal adenocarcinoma
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DAVELAAR AL. et al, (2015), International Journal of Oncology, 47, 583 - 591
Aberrant TP53 detected by combining immunohistochemistry and DNA-FISH improves Barrett's esophagus progression prediction: A prospective follow-up study
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Davelaar AL. et al, (2015), Genes, Chromosomes and Cancer, 54, 82 - 90
Immune signaling and regulation in esophageal cancer
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Calpe S. et al, (2014), Annals of the New York Academy of Sciences, 1325, 15 - 22
A pSMAD/CDX2 Complex Is Essential for the Intestinalization of Epithelial Metaplasia
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Mari L. et al, (2014), Cell Reports, 7, 1197 - 1210
Suppression of p21Rac Signaling and Increased Innate Immunity Mediate Remission in Crohn's Disease
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Parikh K. et al, (2014), Science Translational Medicine, 6, 233ra53 - 233ra53
Nano-Curcumin Inhibits Proliferation of Esophageal Adenocarcinoma Cells and Enhances the T Cell Mediated Immune Response
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Milano F. et al, (2013), Frontiers in Oncology, 3
CD5 expression promotes multiple intracellular signaling pathways in B lymphocyte
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Mageed RA. et al, (2012), Autoimmunity Reviews, 11, 795 - 798
Protein phosphorylation and kinome profiling reveal altered regulation of multiple signaling pathways in B lymphocytes from patients with systemic lupus erythematosus
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Taher TE. et al, (2010), Arthritis & Rheumatism, 62, 2412 - 2423
Kinome Profiling of Clinical Cancer Specimens
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Parikh K. and Peppelenbosch MP., (2010), Cancer Research, 70, 2575 - 2578
Comparison of Peptide Array Substrate Phosphorylation of c-Raf and Mitogen Activated Protein Kinase Kinase Kinase 8
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Parikh K. et al, (2009), PLoS ONE, 4, e6440 - e6440
Extracellular ligation-dependent CD45RB enzymatic activity negatively regulates lipid raft signal transduction
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Parikh K. et al, (2009), Blood, 113, 594 - 603
Modulation of Src Activity by Low Molecular Weight Protein Tyrosine Phosphatase During Osteoblast Differentiation
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Zambuzzi WF. et al, (2008), Cellular Physiology and Biochemistry, 22, 497 - 506
Evidence for a Minimal Eukaryotic Phosphoproteome?
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Diks SH. et al, (2007), PLoS ONE, 2, e777 - e777