Recent publications published by researchers at the MRC WIMM.
Can AlphaFold's breakthrough in protein structure help decode the fundamental principles of adaptive cellular immunity?
McMaster B. et al, (2024), Nat Methods
A robust deep learning workflow to predict CD8 + T-cell epitopes.
Lee CH. et al, (2023), Genome Med, 15
A comparison of clustering models for inference of T cell receptor antigen specificity
Hudson D. et al, (2023)
Can we predict T cell specificity with digital biology and machine learning?
Hudson D. et al, (2023), Nat Rev Immunol, 23, 511 - 521
SARS-CoV-2 peptides bind to NKG2D and increase NK cell activity.
Kim H. et al, (2022), Cell Immunol, 371
Spatiotemporal analysis of human intestinal development at single-cell resolution.
Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23
Single-cell atlas of colonic CD8+ T cells in ulcerative colitis.
Corridoni D. et al, (2020), Nat Med, 26, 1480 - 1490
In silico identification of vaccine targets for 2019-nCoV.
Lee CH. and Koohy H., (2020), F1000Res, 9
Potential CD8+ T Cell Cross-Reactivity Against SARS-CoV-2 Conferred by Other Coronavirus Strains.
Lee CH. et al, (2020), Front Immunol, 11
Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors.
Lee CH. et al, (2020), Front Immunol, 11
Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.
O'Byrne S. et al, (2019), Blood, 134, 1059 - 1071
Colonic epithelial cell diversity in health and inflammatory bowel disease.
Parikh K. et al, (2019), Nature, 567, 49 - 55
Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.
Kinchen J. et al, (2018), Cell, 175, 372 - 386.e17
Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination.
Matheson LS. et al, (2017), Front Immunol, 8
Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination.
Bolland DJ. et al, (2016), Cell Rep, 15, 2475 - 2487
A new phosphate-starvation response in fission yeast requires the endocytic function of myosin I.
Petrini E. et al, (2015), J Cell Sci, 128, 3707 - 3713
A lesson from the ice bucket challenge: using social networks to publicize science.
Koohy H. and Koohy B., (2014), Front Genet, 5