Recent publications published by researchers at the MRC WIMM.
Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics.
Bano F. et al, (2025), Nat Commun, 16
Lymphatic trafficking of immune cells and insights for cancer metastasis.
Jackson DG., (2024), Clin Exp Metastasis, 41, 381 - 386
Aselli Award Winner 2023: The Life and Times of a Lymphomaniac.
Jackson DG., (2023), Lymphology, 56, 92 - 98
Immune Cell Trafficking in the Lymphatics, Hyaluronan Biology and Tumour Metastasis
Jackson DG., (2022), Cancer Metastasis Through the Lymphovascular System, 231 - 240
Hyaluronan and Its Receptors: Key Mediators of Immune Cell Entry and Trafficking in the Lymphatic System.
Johnson LA. and Jackson DG., (2021), Cells, 10
Dendritic cell entry to lymphatic capillaries is orchestrated by CD44 and the hyaluronan glycocalyx.
Johnson LA. et al, (2021), Life Sci Alliance, 4
British Society for Matrix Biology Autumn 2020 Meeting: "Basement Membranes in Health and Disease".
(2021), Int J Exp Pathol, 102, 113 - 135
Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart.
Cahill TJ. et al, (2021), Development, 148
D-Net: An AI model for aligning volumes, developed for cartilage segmentation from CT scans contrasted with a type II collagen binding peptide containing di-iodotyrosine
Zheng JQ. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, 134 - 135
Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection.
Siggins MK. et al, (2020), Nat Commun, 11
The cortical actin network regulates avidity-dependent binding of hyaluronan by the lymphatic vessel endothelial receptor LYVE-1.
Stanly TA. et al, (2020), J Biol Chem, 295, 5036 - 5050
Hyaluronan derived from the limbus is a key Regulator of Corneal Lymphangiogenesis
Sun M. et al, (2020), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61
TNF-derived peptides inhibit tumour growth and metastasis through cytolytic effects on tumour lymphatics.
Lu W. et al, (2019), Clin Exp Immunol, 198, 198 - 211
Hyaluronan in the lymphatics: The key role of the hyaluronan receptor LYVE-1 in leucocyte trafficking.
Jackson DG., (2019), Matrix Biol, 78-79, 219 - 235
Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.
Sun M. et al, (2019), Invest Ophthalmol Vis Sci, 60, 1050 - 1062
Leucocyte Trafficking via the Lymphatic Vasculature- Mechanisms and Consequences.
Jackson DG., (2019), Front Immunol, 10
Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.
Lim HY. et al, (2018), Immunity, 49, 326 - 341.e7