Recent publications published by researchers at the MRC WIMM.
Immune cell trafficking in the lymphatics, hyaluronan biology and tumour metastasis
Chapter
JACKSON DG., (2020), Cancer Metastasis through the Lymphovascular system
Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection.
Journal article
Siggins MK. et al, (2020), Nat Commun, 11
Hyaluronan derived from the limbus is a key Regulator of Corneal Lymphangiogenesis
Conference paper
Sun M. et al, (2020), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61
The cortical actin network regulates avidity-dependent binding of hyaluronan by the lymphatic vessel endothelial receptor LYVE-1.
Journal article
Stanly TA. et al, (2020), J Biol Chem, 295, 5036 - 5050
Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart
Journal article
Cahill TJ. et al, (2020), Development
TNF-derived peptides inhibit tumour growth and metastasis through cytolytic effects on tumour lymphatics.
Journal article
Lu W. et al, (2019), Clin Exp Immunol, 198, 198 - 211
Hyaluronan in the lymphatics: The key role of the hyaluronan receptor LYVE-1 in leucocyte trafficking.
Journal article
Jackson DG., (2019), Matrix Biol, 78-79, 219 - 235
Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.
Journal article
Sun M. et al, (2019), Invest Ophthalmol Vis Sci, 60, 1050 - 1062
Leucocyte Trafficking via the Lymphatic Vasculature- Mechanisms and Consequences.
Journal article
Jackson DG., (2019), Front Immunol, 10
Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.
Journal article
Lim HY. et al, (2018), Immunity, 49, 326 - 341.e7
The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction.
Journal article
Vieira JM. et al, (2018), J Clin Invest, 128, 3402 - 3412
Lymphatic exosomes promote dendritic cell migration along guidance cues.
Journal article
Brown M. et al, (2018), J Cell Biol, 217, 2205 - 2221
TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides.
Journal article
Bauer J. et al, (2018), J Mol Med (Berl), 96, 199 - 209
Developmental Programming of the Cardiac Lymphatics towards improved Heart Repair
Conference paper
Norman S. et al, (2017), HUMAN GENE THERAPY, 28, A5 - A5
The role of the actin cytoskeleton in regulating receptor dynamics and function
Conference paper
Stanly TA. et al, (2017), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 46, S378 - S378
Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium.
Journal article
Banerji S. et al, (2016), J Biol Chem, 291, 25004 - 25018
Lymphatic Regulation of Cellular Trafficking
Journal article
Jackson DG., (2016), J Clin Cell Immunol
A single molecule assay to probe monovalent and multivalent bonds between hyaluronan and its key leukocyte receptor CD44 under force.
Journal article
Bano F. et al, (2016), Sci Rep, 6
Critical importance of appropriate fixation conditions for faithful imaging of receptor microclusters.
Journal article
Stanly TA. et al, (2016), Biol Open, 5, 1343 - 1350
Micromechanical Analysis of the Hyaluronan-Rich Matrix Surrounding the Oocyte Reveals a Uniquely Soft and Elastic Composition.
Journal article
Chen X. et al, (2016), Biophys J, 110, 2779 - 2789