Recent publications published by researchers at the MRC WIMM.
Lymphatic trafficking of immune cells and insights for cancer metastasis.
Jackson DG., (2023), Clin Exp Metastasis
Hyaluronan and Its Receptors: Key Mediators of Immune Cell Entry and Trafficking in the Lymphatic System.
Johnson LA. and Jackson DG., (2021), Cells, 10
Hyaluronan derived from the limbus is a key regulator of corneal lymphangiogenesis
Sun M. et al, (2021), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 102, 127 - 127
Dendritic cell entry to lymphatic capillaries is orchestrated by CD44 and the hyaluronan glycocalyx
JOHNSON L. et al, (2021), Life Science Alliance
Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart.
Cahill TJ. et al, (2021), Development, 148
Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart
VIEIRA J. et al, (2021), Development
Immune cell trafficking in the lymphatics, hyaluronan biology and tumour metastasis
JACKSON DG., (2020), Cancer Metastasis through the Lymphovascular system
Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection.
Siggins MK. et al, (2020), Nat Commun, 11
Hyaluronan derived from the limbus is a key Regulator of Corneal Lymphangiogenesis
Sun M. et al, (2020), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61
The cortical actin network regulates avidity-dependent binding of hyaluronan by the lymphatic vessel endothelial receptor LYVE-1.
Stanly TA. et al, (2020), J Biol Chem, 295, 5036 - 5050
TNF-derived peptides inhibit tumour growth and metastasis through cytolytic effects on tumour lymphatics.
Lu W. et al, (2019), Clin Exp Immunol, 198, 198 - 211
Hyaluronan in the lymphatics: The key role of the hyaluronan receptor LYVE-1 in leucocyte trafficking.
Jackson DG., (2019), Matrix Biol, 78-79, 219 - 235
Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.
Sun M. et al, (2019), Invest Ophthalmol Vis Sci, 60, 1050 - 1062
Leucocyte Trafficking via the Lymphatic Vasculature- Mechanisms and Consequences.
Jackson DG., (2019), Front Immunol, 10
Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.
Lim HY. et al, (2018), Immunity, 49
Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.
Lim HY. et al, (2018), Immunity, 49, 326 - 341.e7
The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction.
Vieira JM. et al, (2018), J Clin Invest, 128, 3402 - 3412
Lymphatic exosomes promote dendritic cell migration along guidance cues.
Brown M. et al, (2018), J Cell Biol, 217, 2205 - 2221
TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides.
Bauer J. et al, (2018), J Mol Med (Berl), 96, 199 - 209