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Publications

Recent publications published by researchers at the MRC WIMM.

Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation.

Chen Y-L. et al, (2023), Sci Immunol, 8

CD1a promotes systemic manifestations of skin inflammation.

Hardman CS. et al, (2022), Nat Commun, 13

Dengue virus co-opts innate type 2 pathways to escape early control of viral replication.

Fonseka CL. et al, (2022), Commun Biol, 5

IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent.

Hardman CS. et al, (2021), Sci Immunol, 6

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype.

Fraser E. et al, (2021), Front Immunol, 12

Innate Lymphocyte Mechanisms in Skin Diseases.

Chen Y-L. et al, (2020), 38, 171 - 202

Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation.

Chen Y-L. et al, (2020), J Exp Med, 217

Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells.

Luo J. et al, (2019), J Allergy Clin Immunol, 144, 1722 - 1726.e10

Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis.

Chen Y-L. et al, (2019), Sci Transl Med, 11

A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue.

Rana BMJ. et al, (2019), J Exp Med, 216, 1999 - 2009

Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function.

Hardman C. et al, (2019), J Allergy Clin Immunol, 143, 2329 - 2333

Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection.

Jayathilaka D. et al, (2018), Nat Commun, 9

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection.

Wijeratne DT. et al, (2018), PLoS Negl Trop Dis, 12

Cutaneous bacterial sensing through group 2 innate lymphoid cell presentation of endogenous CD1a lipid antigens

Hardman C. et al, (2018), BRITISH JOURNAL OF DERMATOLOGY, 178, E403 - E403

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.

Hardman CS. et al, (2017), Sci Immunol, 2

Filaggrin inhibits house dust mite phospholipase generation of CD1a lipid antigens for recognition by T cells

Jarrett R. et al, (2016), BRITISH JOURNAL OF DERMATOLOGY, 175, 50 - 50

Interleukin-33, friend and foe in type-2 immune responses.

Hardman C. and Ogg G., (2016), Curr Opin Immunol, 42, 16 - 24

Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase

Jarrett R. et al, (2016), BRITISH JOURNAL OF DERMATOLOGY, 174, E49 - E50

Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production.

Salimi M. et al, (2016), J Immunol, 196, 45 - 54

IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction

Barlow JL. et al, (2013), Journal of Allergy and Clinical Immunology, 132, 933 - 941

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