Recent publications published by researchers at the MRC WIMM.
Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses.
Yang Y. et al, (2025), Nat Commun, 16
Repeated plague infections across six generations of Neolithic Farmers
Seersholm FV. et al, (2024), Nature
Ancient DNA reveals evolutionary origins of autoimmune diseases.
Barrie W. et al, (2024), Nat Rev Immunol
Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations.
Barrie W. et al, (2024), Nature, 625, 321 - 328
The selection landscape and genetic legacy of ancient Eurasians.
Irving-Pease EK. et al, (2024), Nature, 625, 312 - 320
Acute Inflammatory Diseases of the Central Nervous System After SARS-CoV-2 Vaccination.
Francis AG. et al, (2023), Neurol Neuroimmunol Neuroinflamm, 10
Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Pymm P. et al, (2022), Cell Reports, 38
ACUTE INFLAMMATORY CNS DISEASES FOLLOWING VACCINATION AGAINST SARS-COV-2
Francis A. et al, (2022), JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 93
Elevated genetic risk for multiple sclerosis originated in Steppe Pastoralist populations
Barrie W. et al, (2022)
A simple, safe and sensitive method for SARS-CoV-2 inactivation and RNA extraction for RT-qPCR
Kalnina L. et al, (2021), APMIS
Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient.
Wurm H. et al, (2020), Mult Scler, 26, 1261 - 1264
HIV-1 p24Gag adaptation to modern and archaic HLA-allele frequency differences in ethnic groups contributes to viral subtype diversification.
Kist NC. et al, (2020), Virus Evol, 6
HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression.
Chang C-H. et al, (2015), Sci Rep, 5
Possible footprints of APOBEC3F and/or other APOBEC3 deaminases, but not APOBEC3G, on HIV-1 from patients with acute/early and chronic infections.
Armitage AE. et al, (2014), J Virol, 88, 12882 - 12894
HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification.
Tenzer S. et al, (2014), Cell Rep, 7, 448 - 463
HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification
Tenzer S. et al, (2014), Cell Reports, 7, 448 - 463
APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon.
Armitage AE. et al, (2012), PLoS Genet, 8
Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.
Schmidt J. et al, (2012), PLoS Pathog, 8
Acute cytomegalovirus infection in Kenyan HIV-infected infants.
Slyker JA. et al, (2009), AIDS, 23, 2173 - 2181
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance.
Tenzer S. et al, (2009), Nat Immunol, 10, 636 - 646