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Recent publications published by researchers at the MRC WIMM.

HSV-1 employs UL56 to antagonize expression and function of cGAMP channels.

Journal article

Blest HTW. et al, (2024), Cell Rep, 43

Varicella-Zoster virus ORF9 is an antagonist of the DNA sensor cGAS.

Journal article

Hertzog J. et al, (2022), EMBO J, 41

Interferon induction held captive in tumor cells.

Journal article

Bridgeman A. and Rehwinkel J., (2021), Mol Cell, 81, 4109 - 4110

Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.

Journal article

Chauveau L. et al, (2021), EMBO Rep, 22

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.

Journal article

Clapes T. et al, (2021), Nat Cell Biol, 23, 704 - 717

The RNA sensor MDA5 detects SARS-CoV-2 infection.

Journal article

Sampaio NG. et al, (2021), Sci Rep, 11

cGAMP loading enhances the immunogenicity of VLP vaccines

Journal article

Chauveau L. et al, (2020)

Deoxyguanosine is a TLR7 agonist.

Journal article

Davenne T. et al, (2020), Eur J Immunol, 50, 56 - 62

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.

Journal article

Glück S. et al, (2017), Nat Cell Biol, 19, 1061 - 1070

Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.

Journal article

Maelfait J. et al, (2017), EMBO J, 36, 2529 - 2543

Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture.

Journal article

Mayer A. et al, (2017), Methods Mol Biol, 1656, 143 - 152

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.

Journal article

Maelfait J. et al, (2016), Cell Rep, 16, 1492 - 1501

Viruses transfer the antiviral second messenger cGAMP between cells.

Journal article

Bridgeman A. et al, (2015), Science, 349, 1228 - 1232

Characterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c mice.

Journal article

Ondondo B. et al, (2014), Clin Vaccine Immunol, 21, 1565 - 1572

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

Journal article

Borthwick N. et al, (2014), Mol Ther, 22, 464 - 475

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