Recent publications published by researchers at the MRC WIMM.
A human genome editing-based MLL::AF4 B-cell ALL model recapitulates key cellular and molecular leukemogenic features.
Journal article
Bueno C. et al, (2023), Blood
Temporal analyses reveal a pivotal role for sense and antisense enhancer RNAs in coordinate immunoglobulin lambda locus activation.
Journal article
Gao Z. et al, (2023), Nucleic Acids Res
MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Journal article
Crump NT. et al, (2023), Nat Commun, 14
Author Correction: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.
Journal article
Downes DJ. et al, (2023), Nat Protoc
Dysregulation of chromatin via H3K27 methylation underpins differentiation arrest in Isocitrate dehydrogenase-mutant Acute Myeloid Leukaemia
Preprint
Silveira DRA. et al, (2023)