N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells

Emms VL.; Lewis LA.; Beja L.; Bulman NFA.; Pires E.; Muskett FW.; McCullagh JSO.; Swift LP.; McHugh PJ.; Hopkinson RJ.

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N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells

Emms VL., Lewis LA., Beja L., Bulman NFA., Pires E., Muskett FW., McCullagh JSO., Swift LP., McHugh PJ., Hopkinson RJ.

N-Acyloxymethyl-phthalimides are esterase-sensitive chemical tools that enable controllable delivery of formaldehyde to human cells.

Original publication

DOI

10.1039/d3sc02867d

Type

Journal article

Journal

Chemical Science

Publisher

Royal Society of Chemistry (RSC)

Publication Date

2023