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Publications

Recent publications published by the researchers at the MRC WIMM.

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.

Gooding S. et al, (2019), Nat Commun, 10

Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation.

Yu X. et al, (2019), Elife, 8

HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly

Favard C. et al, (2019), Science Advances, 5, eaaw8651 - eaaw8651

High photon count rate super-resolution fluorescence fluctuation spectroscopy

Schneider F. et al, (2019)

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.

Harnack C. et al, (2019), Nat Commun, 10

Scoring a HAT-Trick against Lymphoma

Bannard O., (2019), Immunity, 51, 420 - 423

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions.

Leng T. et al, (2019), Cell Rep, 28, 3077 - 3091.e5

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M. et al, (2019), Cancer Cell, 36

Improving the diagnosis and classification of Ph-negative myeloproliferative neoplasms through deep phenotyping

Sirinukunwattana K. et al, (2019)

Persistence of skewed X-chromosome inactivation in pre-B acute lymphoblastic leukemia of a female ATRX mutation carrier.

Bradley CP. et al, (2019), Blood Adv, 3, 2627 - 2631

Cardiovascular Manifestations of Systemic Sclerosis: A Danish Nationwide Cohort Study.

Butt SA. et al, (2019), J Am Heart Assoc, 8

Mutant IDH1 Inhibitor Ivosidenib (IVO; AG-120) in Combination with Azacitidine (AZA) for Newly Diagnosed Acute Myeloid Leukemia (ND AML)

DiNardo CD. et al, (2019), CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 19, S217 - S218

Changes in micronutrient and inflammation serum biomarker concentrations after a norovirus human challenge

Williams AM. et al, (2019), The American Journal of Clinical Nutrition

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T-cells.

Saliba DG. et al, (2019), Elife, 8

Modelling erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I)

Scott C. et al, (2019)

Identification of host-pathogen-disease relationships using a scalable Multiplex Serology platform in UK Biobank

Mentzer A. et al, (2019)

Nanoscale dynamics of cholesterol in the cell membrane.

Pinkwart K. et al, (2019), J Biol Chem, 294, 12599 - 12609

Elevated CD54 expression renders CD4+ T cells susceptible to NK cell-mediated killing.

Chen X. et al, (2019), J Infect Dis

Optimised oligonucleotide substrates to assay XPF ERCC1 nuclease activity for the discovery of DNA repair inhibitors†

MCHUGH PJ. et al, (2019), Chemical Communications

A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice.

Gawenis LR. et al, (2019), Scientific reports, 9

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