Recent publications published by researchers at the MRC WIMM.
Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis.
Sun B. et al, (2025), Sci Adv, 11
Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation
Hosseini A. et al, (2025), Nature
Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution.
Mimpen JY. et al, (2025), J Physiol
Is Enhancer Function Driven by Protein-Protein Interactions? From Bacteria to Leukemia.
Crump NT. and Milne TA., (2025), Bioessays
Active regulatory elements recruit cohesin to establish cell specific chromatin domains.
Georgiades E. et al, (2025), Sci Rep, 15
Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection
Preechanukul J. et al, (2025)
Efficacy of a Novel BCL-xL Degrader, DT2216, in Preclinical Models of JAK2-mutated Post-MPN AML.
Wang Z. et al, (2025), Blood
DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition.
Ayyadevara VSSA. et al, (2025), Leukemia
Pharmacological targeting of BMAL1 modulates circadian and immune pathways.
Pu H. et al, (2025), Nat Chem Biol
Lambda Red Recombineering of Bacteriophage in the Lysogenic State. In Methods in Molecular Biology
Tridgett M. et al, (2025), Methods in molecular biology (Clifton, N.J.)
Scarless Recombineering of Phage in Lysogenic State
Ababi M. et al, (2025), Methods in molecular biology (Clifton, N.J.)
Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses.
Yang Y. et al, (2025), Nat Commun, 16
Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics.
Bano F. et al, (2025), Nat Commun, 16
Author Correction: The α-globin super-enhancer acts in an orientation-dependent manner.
Kassouf MT. et al, (2025), Nat Commun, 16
ADAR1 in lenalidomide resistance: still immunomodulation?
Gooding S., (2025), Blood, 145, 1104 - 1106
Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis
Tram TTB. et al, (2025)
The Power of Mouse Models in the Diagnostic Odyssey of Patients with Rare Congenital Anomalies
Twigg S., (2025), Mammalian Genome