Recent publications published by researchers at the MRC WIMM.
T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination.
Chen J-L. et al, (2025), Nat Commun, 16
Resistance to immunomodulatory drugs in multiple myeloma: the cereblon pathway and beyond
Teoh PJ. et al, (2025), Haematologica, 110, 1074 - 1091
The Structural Biology of T-Cell Antigen Detection at Close Contacts.
Lui Y. et al, (2025), Immunol Rev, 331
CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade
Milotay G. et al, (2025), Nature Medicine
Biallelic FGF4 Variants Linked to Thoracic Dystrophy and Respiratory Insufficiency.
Watts LM. et al, (2025), Clin Genet
Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria.
Cacace E. et al, (2025), Nat Commun, 16
Genome-wide association study of somatic GATA1s mutations in newborns with Down Syndrome.
Li Y. et al, (2025), Blood Adv
Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states.
Li A. et al, (2025), Cell Rep, 44
Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation.
Hosseini A. et al, (2025), Nature
Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution.
Mimpen JY. et al, (2025), J Physiol
Is Enhancer Function Driven by Protein-Protein Interactions? From Bacteria to Leukemia.
Crump NT. and Milne TA., (2025), Bioessays
Active regulatory elements recruit cohesin to establish cell specific chromatin domains.
Georgiades E. et al, (2025), Sci Rep, 15
Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection
Preechanukul J. et al, (2025)
Learning and teaching biological data science in the Bioconductor community.
Drnevich J. et al, (2025), PLoS Comput Biol, 21
Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1.
Agarwal P. et al, (2025), Nature
Efficacy of a Novel BCL-xL Degrader, DT2216, in Preclinical Models of JAK2-mutated Post-MPN AML.
Wang Z. et al, (2025), Blood