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Publications

Recent publications published by researchers at the MRC WIMM.

High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint pathway at the primary tumour site of breast cancer.

Kawashima M. et al, (2019), British journal of cancer

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.

Lord SR. et al, (2019), British journal of cancer

ATR-16 Syndrome: Mechanisms Linking Monosomy to Phenotype

BABBS C. et al, (2019), Journal of Medical Genetics

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages.

Ling ITC. and Sauka-Spengler T., (2019), Nature cell biology, 21, 1504 - 1517

A genome-wide assessment of the ancestral neural crest gene regulatory network

Hockman D. et al, (2019), Nature Communications, 10

Oncogenic Drivers and Development.

Cruz Hernandez D. and Vyas P., (2019), Cancer discovery, 9, 1653 - 1655

Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.

Braun TP. et al, (2019), Nat Commun, 10

A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus.

Oudelaar AM. et al, (2019), Nat Commun, 10

GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome.

Garnett C. et al, (2019), IUBMB Life

Self-maintaining CD103+ cancer-specific T cells are highly energetic with rapid cytotoxic and effector responses.

Abd Hamid M. et al, (2019), Cancer Immunol Res

ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile.

Favara DM. et al, (2019), Metabolites, 9

High glucose concentrations mask cellular phenotypes in a stem cell model of tuberous sclerosis complex.

Rocktäschel P. et al, (2019), Epilepsy Behav

Broadly inhibiting anti-neuraminidase monoclonal antibodies induced by trivalent influenza vaccine and H7N9 infection in humans.

Rijal P. et al, (2019), J Virol

Semaphorin 3A induces cytoskeletal paralysis in tumor-specific CD8+ T cells

Barnkob M. et al, (2019)

More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains

Azbazdar Y. et al, (2019), Frontiers in Cell and Developmental Biology, 7

B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2.

du Pré MF. et al, (2019), The Journal of experimental medicine

Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation

Chen Y-L. et al, (2019), Journal of Experimental Medicine

Genetic variation in CFTR and modifier loci may modulate cystic fibrosis disease severity.

Paranjapye A. et al, (2019), J Cyst Fibros

A Single and Un-Adjuvanted Dose of a Chimpanzee Adenovirus-Vectored Vaccine against Chikungunya Virus Fully Protects Mice from Lethal Disease.

Kroon Campos R. et al, (2019), Pathogens, 8

Broadly inhibiting anti-neuraminidase monoclonal antibodies induced by 1 trivalent influenza vaccine and H7N9 infection in humans

RIJAL P. and TOWNSEND A., (2019), Journal of Virology

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