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Publications

Recent publications published by researchers at the MRC WIMM.

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

Luis TC. et al, (2023), Nature Communications, 14

The management of myelofibrosis: A British Society for Haematology Guideline.

McLornan DP. et al, (2023), Br J Haematol

Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis.

Fang Z. et al, (2023), Nat Commun, 14

Tracking early mammalian organogenesis - prediction and validation of differentiation trajectories at whole organism scale.

Imaz-Rosshandler I. et al, (2023), Development

Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial.

Freeman SD. et al, (2023), Blood, 142, 1697 - 1707

Detailed Analysis of ITPR1 Missense Variants Guides Diagnostics and Therapeutic Design.

Tolonen JP. et al, (2023), Mov Disord

Outcomes and Characteristics of Non-Melanoma Skin Cancers in Patients with Myeloproliferative Neoplasms on Ruxolitinib.

Rampotas A. et al, (2023), Blood

Changing treatment changing prognosis of mutations

Vyas P., (2023), Blood, 142, 1583 - 1585

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.

Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632

Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases.

Pagnamenta AT. et al, (2023), Genome Med, 15

Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.

Weeratunga P. et al, (2023), Nat Commun, 14

Germinal centers output clonally diverse plasma cell populations expressing high- and low-affinity antibodies.

Sprumont A. et al, (2023), Cell

Diagnosis and evaluation of prognosis of myelofibrosis: A British Society for Haematology Guideline.

McLornan DP. et al, (2023), Br J Haematol

Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism.

Pham VN. et al, (2023), Science, 382

Probing long COVID through a proteomic lens: a comprehensive two-year longitudinal cohort study of hospitalised survivors.

Gu X. et al, (2023), EBioMedicine, 98

Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids

AHMED A., (2023), Cell Reports

Absolute risk estimation of new-onset proteinuria in patients with systemic lupus erythematosus: a Danish nationwide cohort study.

Andersen M. et al, (2023), Clin Exp Rheumatol, 41, 2264 - 2268

Effects of glycation end-products on the dental pulp in patients with type 2 diabetes.

Alsamahi S. et al, (2023), Int Endod J, 56, 1373 - 1384

Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts.

Moura PL. et al, (2023), Cancer research

IgG1-3 MuSK Antibodies Inhibit AChR Cluster Formation, Restored by SHP2 Inhibitor, Despite Normal MuSK, DOK7, or AChR Subunit Phosphorylation.

Cao M. et al, (2023), Neurol Neuroimmunol Neuroinflamm, 10

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