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Publications

Recent publications published by researchers at the MRC WIMM.

A cluster of type II interferon-regulated genes associates with disease activity in patients with systemic lupus erythematosus

Siddiqi KZ. et al, (2022), Journal of Autoimmunity, 132

Left ventricular size and function in patients with systemic lupus erythematosus associate with lupus anticoagulant: An echocardiographic follow-up study

Myhr KA. et al, (2022), Journal of Autoimmunity, 132

Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors.

Ma K. et al, (2022), J Immunol

Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells

Torres JM. et al, (2022)

Whole genome sequencing of ‘mutation-negative’ individuals with Cornelia de Lange Syndrome

Ansari M. et al, (2022)

Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties.

Ragaller F. et al, (2022), Open biology, 12

Influence of the extracellular domain size on the dynamic behavior of membrane proteins.

Gurdap CO. et al, (2022), Biophysical journal

IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.

Clement M. et al, (2022), Nat Commun, 13

Lymphatic endothelia stakeout cryptic stem cells.

Antanaviciute A. et al, (2022), Cell Stem Cell, 29, 1292 - 1293

A tubulin binding molecule drives differentiation of acute myeloid leukemia cells.

Jackson TR. et al, (2022), iScience, 25

Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction.

Hadjihambi A. et al, (2022), J Hepatol

Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.

Groelly FJ. et al, (2022), Mol Cell

Identification and characterization of in vitro expanded hematopoietic stem cells.

Che JLC. et al, (2022), EMBO reports

Clonal behaviour of myogenic precursor cells throughout the vertebrate lifespan.

Hughes SM. et al, (2022), Biol Open, 11

Deep sequencing of short capped RNAs reveals novel families of noncoding RNAs.

De Hoon MJL. et al, (2022), Genome Res

Phase III MANIFEST-2: pelabresib + ruxolitinib vs placebo + ruxolitinib in JAK inhibitor treatment-naive myelofibrosis.

Harrison CN. et al, (2022), Future Oncol

Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells

Parmigiani E. et al, (2022), Developmental Cell, 57, 1847 - 1865.e9

Donor natural killer cells trigger production of beta-2-microglobulin to enhance post bone marrow transplant immunity.

Ruggeri L. et al, (2022), Blood

Single Cell Transcriptomics identifies a WNT7A-FZD5 Signaling Axis that maintains Fallopian Tube Stem Cells in Patient-derived Organoids

Alsaadi A. et al, (2022)

Phase Ib study of eltrombopag and azacitidine in patients with high-risk myelodysplastic syndromes and related disorders (the ELASTIC study).

Sternberg A. et al, (2022), Br J Haematol

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