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Publications (9244)

Recent publications published by the researchers at the MRC WIMM.

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.

Morotti M. et al, (2019), Proc Natl Acad Sci U S A

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.

van Bemmel JG. et al, (2019), Nat Genet

Germline selection shapes human mitochondrial DNA diversity.

Wei W. et al, (2019), Science (New York, N.Y.), 364

Single-Cell and Time-Resolved Profiling of Intracellular Salmonella Metabolism in Primary Human Cells.

Xu J. et al, (2019), Anal Chem

Why are so many MLL lysine methyltransferases required for normal mammalian development?

Crump NT. and Milne TA., (2019), Cell Mol Life Sci

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection.

Rigby RE. et al, (2019), Sci Rep, 9

Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate.

Palii CG. et al, (2019), Cell Stem Cell, 24, 812 - 820.e5

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

Kennedy NA. et al, (2019), The Lancet Gastroenterology and Hepatology, 4, 341 - 353

The p.H63D allele of the HFE gene protects against low iron stores in Sri Lanka.

Allen A. et al, (2019), Blood Cells Mol Dis, 76, 72 - 77

Identification of two distinct pathways of human myelopoiesis.

Drissen R. et al, (2019), Science immunology, 4

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8T Cell Responses

Corridoni D. et al, (2019), FRONTIERS IN IMMUNOLOGY, 10

Variation in PU.1 binding and chromatin looping at neutrophil enhancers influences autoimmune disease susceptibility

Watt S. et al, (2019)

A recurrent activating missense mutation in Waldenström macroglobulinemia affects the DNA binding of the ETS transcription factor SPI1 and enhances proliferation.

Roos-Weil D. et al, (2019), Cancer Discov

Sequencing of human genomes with nanopore technology.

Bowden R. et al, (2019), Nature communications, 10

Becalming Type 17 Inflammation in Ulcerative Colitis.

Chen HH. and Simmons A., (2019), Immunity, 50, 1029 - 1031

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.

Di Genua C. et al, (2019), Haematologica

Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.

Axmann M. et al, (2019), Nano Lett, 19, 2562 - 2567

Surfaceome interrogation using an RNA-seq approach highlights leukemia initiating cell biomarkers in an LMO2 T cell transgenic model.

Pais H. et al, (2019), Sci Rep, 9

De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder.

Calpena E. et al, (2019), Am J Hum Genet, 104, 709 - 720

Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.

Schwartz C. et al, (2019), Allergy

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