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Publications

Recent publications published by researchers at the MRC WIMM.

Quantum mechanical electronic and geometric parameters for DNA k-mers as features for machine learning

Masuda K. et al, (2023)

MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses

Heuberger CE. et al, (2023)

Tissue-resident memory T cells in pancreatic ductal adenocarcinoma co-express PD-1 and TIGIT and functional inhibition is reversible by dual antibody blockade.

Pearce H. et al, (2023), Cancer Immunol Res

Career success for women academics in higher education: Choices and challenges

OBERS N., (2023), South African Journal of Higher Education

IFNγ signaling in cytotoxic T cells restricts anti-tumor responses by inhibiting the maintenance and diversity of intra-tumoral stem-like T cells.

Mazet JM. et al, (2023), Nat Commun, 14

Lymphatic vessels in bone support regeneration after injury.

Biswas L. et al, (2023), Cell, 186, 382 - 397.e24

Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.

Huang K-YA. et al, (2023), Nat Commun, 14

Correction: Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients.

Ryou H. et al, (2023), Leukemia

Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.

Kurata K. et al, (2023), Blood Cancer J, 13

Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-Like Autoimmunity.

Hodgson R. et al, (2023), J Immunol

In silico engineering a CD80 variant with increased affinity to CTLA-4 and decreased affinity to CD28 for optimized cancer immunotherapy.

Hajihassan Z. et al, (2023), J Immunol Methods, 513

Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.

Matute JD. et al, (2023), J Exp Med, 220

Acute Inflammatory Diseases of the Central Nervous System After SARS-CoV-2 Vaccination.

Francis AG. et al, (2023), Neurol Neuroimmunol Neuroinflamm, 10

Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.

Moll T. et al, (2023), Life Sci Alliance, 6

Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia.

Rastogi N. et al, (2022), Leukemia

Ex Vivo Expansion and Genetic Manipulation of Mouse Hematopoietic Stem Cells in Polyvinyl Alcohol-Based Cultures

Khoo HM. et al, (2022), Journal of Visualized Experiments

Generalised interrelations among mutation rates drive the genomic compliance of Chargaff’s second parity rule

Pflughaupt P. and Sahakyan AB., (2022)

Prospective Assessment of Tumour Burden and Bone Disease in Plasma Cell Dyscrasias Using DW-MRI and Exploratory Bone Biomarkers.

Agarwal G. et al, (2022), Cancers (Basel), 15

Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.

Monnot GC. et al, (2022), Nat Immunol

Craniosynostosis, inner ear, and renal anomalies in a child with complete loss of SPRY1 (sprouty homolog 1) function.

Tooze RS. et al, (2022), J Med Genet

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