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Contact information


yin.dong@ndcn.ox.ac.uk

Biography

Yin Dong studied biochemistry at the University of Warwick for his undergraduate degree, before undertaking a PhD at the University of Birmingham under the supervision of Prof Karen Morrison. He then worked at the Structural Genomics Consortium as a post-doctoral research associate with Prof Liz Carpenter. He won a MRC Career Development Fellowship to start his independent research at the Nuffield Department of Clinical Neurosciences under the mentorship of Prof David Beeson, working in the Weatherall Institute of Molecular Medicine. 

Yin Yao Dong

PhD, Bsc

Associate Professor

  • Head of Neurosciences Group at the WIMM
  • Manager of functional diagnostics for the National Referral Service for Congenital Myasthenic Syndromes.

My research is focused on diseases of the neuromuscular junction

Research

My reasearch is focused on the neuromuscular junction, which is the cholinergic synapse between motor neurons and skeletal muscles that enables all voluntary movement. I use my diverse training in biochemistry, molecular biology, and structural biology to lead a multidisciplined team studying the biology of this synapse in normal and different disease states like genetic (including congenital) myasthenic syndromes and congenital disorders of glycosylation.

We work closely with a range of collaborators in academia and industry, as well as clinicians and charities to translate our research into benefits for patients. We carry out functional testing of genetic variants of unknown significance to help doctors diagnose genetic disorders. We also work with industrial collaborators to determine if new treatments they develop improve the symptoms of disease in a variety of experimental models.

Key publications

Recent publications

More publications