Peter McHugh
D.Phil
Professor of Molecular Oncology
The study of DNA damage and repair to understand the causes of cancer and improve its treatment.
Brief Biography
Director, Oncology Laboratories, WIMM
Head, DNA Damage and Repair Group, Department of Oncology and WIMM
Royal Society Research Fellow, UCL, 2001-2002
Post-Doctoral Fellow, UCL, 1997-2001
D.Phil, University of Oxford 1996
Recent publications
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XPF-ERCC1: Linchpin of DNA crosslink repair.
Journal article
McHugh PJ., (2020), PLoS Genet, 16
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Analysis of DNA Interstrand Cross-Links and their Repair by Modified Comet Assay.
Chapter
Swift LP. et al, (2020), 2119, 79 - 88
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Optimised oligonucleotide substrates to assay XPF-ERCC1 nuclease activity for the discovery of DNA repair inhibitors.
Journal article
Thomas AM. et al, (2019), Chem Commun (Camb), 55, 11671 - 11674
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A hydroxamic-acid-containing nucleoside inhibits DNA repair nuclease SNM1A.
Journal article
Doherty W. et al, (2019), Org Biomol Chem, 17, 8094 - 8105
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Microhomologies are prevalent at Cas9-induced larger deletions.
Journal article
Owens DDG. et al, (2019), Nucleic Acids Res, 47, 7402 - 7417