Professor of Molecular Oncology
The study of DNA damage and repair to understand the causes of cancer and improve its treatment.
Director, Oncology Laboratories, WIMM
Head, DNA Damage and Repair Group, Department of Oncology and WIMM
Royal Society Research Fellow, UCL, 2001-2002
Post-Doctoral Fellow, UCL, 1997-2001
D.Phil, University of Oxford 1996
Optimised oligonucleotide substrates to assay XPF ERCC1 nuclease activity for the discovery of DNA repair inhibitors†
MCHUGH PJ. et al, (2019), Chemical Communications
A hydroxamic-acid-containing nucleoside inhibits DNA repair nuclease SNM1A.
Doherty W. et al, (2019), Org Biomol Chem
Microhomologies are prevalent at Cas9-induced larger deletions.
Owens DDG. et al, (2019), Nucleic acids research, 47, 7402 - 7417
Antiviral activity of bone morphogenetic proteins and activins.
Eddowes LA. et al, (2019), Nat Microbiol, 4, 339 - 351
Squaramide-Based 5’-Phosphate Replacements Bind to the DNA Repair Exonuclease SNM1A
Dürr EM. et al, (2018), ChemistrySelect, 3, 12824 - 12829