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Search results (100)

« Back to Publications

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.

Roddan R. et al, (2025)

Transcription-coupled repair of crosslinking DNA damage.

Roddan R. et al, (2025), DNA Repair (Amst), 152

The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.

Song W. et al, (2025), Nucleic Acids Res, 53

The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.

Song W. et al, (2024)

Molecular insights into the stimulation of SNM1A nuclease activity by CSB during interstrand crosslink processing.

Roddan R. et al, (2024)

SNM1A is crucial for efficient repair of complex DNA breaks in human cells.

Swift LP. et al, (2024), Nat Commun, 15

Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target.

Bielinski M. et al, (2024), Chem Sci, 15, 8227 - 8241

N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells.

Emms VL. et al, (2023), Chem Sci, 14, 12498 - 12505

WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures.

Mengoli V. et al, (2023), EMBO J, 42

SNM1A (DCLRE1A) is crucial for efficient repair of complex DNA breaks in human cells

McHugh P. et al, (2023)

N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells

Emms VL. et al, (2023), CHEMICAL SCIENCE, 14, 12498 - 12505

Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.

Baddock HT. et al, (2022), Nucleic Acids Res, 50, 1484 - 1500

Editorial: Targeting DNA repair and the DNA damage response: Beyond the standard PI3 kinase-like kinases.

Turchi JJ. et al, (2022), Front Oncol, 12

Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.

Yosaatmadja Y. et al, (2021), Nucleic Acids Res, 49, 9310 - 9326

A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.

Baddock HT. et al, (2021), Nucleic Acids Res, 49, 9294 - 9309

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