Contact information
Research groups
Websites
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MRC Human Immunology Unit
Research Unit
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MRC Weatherall Institute of Molecular Medicine
Research Institute
Graham Ogg
Professor of Dermatology
Skin and mucosae frequently represent the first point of contact with pathogens and allergens, yet we still know relatively little of the role of the surface immune system in clearing such challenges. This is crucially important in understanding the mechanisms of skin diseases and related diseases, and for optimising approaches to cutaneous drug and vaccine delivery. The aim of the group is therefore to understand, at the molecular and cellular level, the role of human cutaneous immune responses in mechanisms of disease, treatment and vaccination. As well as contributing to an understanding of disease pathogenesis, we aim to translate our findings to changes in clinical practice.
Recent publications
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Altered monocyte response to the dengue virus in those with varying severity of past dengue infection.
Journal article
Kamaladasa A. et al, (2019), Antiviral Res
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Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis and a history of nonsteroidal immunosuppressant use: a post hoc analysis of the phase III CAFE trial
Conference paper
Bouaziz J-D. et al, (2019), BRITISH JOURNAL OF DERMATOLOGY, 181, 66 - 67
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Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.
Journal article
Schwartz C. et al, (2019), Allergy
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Correction: Synergistic activation of pro-inflammatory type-2 CD8 + T lymphocytes by lipid mediators in severe eosinophilic asthma.
Journal article
Hilvering B. et al, (2019), Mucosal Immunol, 12
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FEVIPIPRANT INHIBITS PROSTAGLANDIN D2 MEDIATED ACTIVATION OF GROUP 2 INNATE LYMPHOID CELLS (ILC2S)
Conference paper
Sandham D. et al, (2019), RESPIROLOGY, 24, 105 - 105