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The mission of the MRC Weatherall Institute of Molecular Medicine (WIMM) is to undertake internationally competitive research into the processes underlying normal cell and molecular biology and to determine the mechanisms by which these processes are perturbed in inherited and acquired human diseases. It is also our mission to translate this research to improve human health. The WIMM is uniquely placed among biomedical institutes throughout the world in its pioneering vision of combining outstanding clinical research with excellent basic science. The WIMM Faculty currently includes an equal mixture of scientists and clinicians working together and in collaboration with the National Institute of Health Research, the NHS and commercial companies with the aim of improving the diagnosis and treatment of human diseases. The major topics of current research include haematology, immunology, stem cell biology, oncology and inherited human genetic diseases. The Institute benefits from strategic support from the MRC.

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The Institute values communication with members of the broader scientific community and the general public and with the support of the Medical Research Council (MRC) we have commissioned three short videos to explain our mission.


Lister Institute Research Prize Fellowship awarded

Lister Institute Research Prize Fellowship awarded

Posted 27/05/2016

Jan Rehwinkel, a Group leader in HIU,  has recently been awarded a Lister Institute Research Prize Fellowship to study “Z-RNA and Z-DNA: Novel Inducers of Antiviral Immunity”.  Jan says “In addition to the well-known B- and A-form, double-stranded DNA and RNA can also adopt the so-called Z-conformation. Z-DNA and Z-RNA are characterised by a left-handed double helix, the absence of major grooves and a zig-zag arrangement of the phosphodiester bac ...


From molecules to microscopes: WIMM Day 2016

From molecules to microscopes: WIMM Day 2016

Posted 18/05/2016

Once a year, all research and support staff working within the MRC Weatherall Institute of Molecular Medicine (WIMM) in Oxford gather together to explore and discuss the innovative and diverse research ongoing within the Institute. The WIMM houses nearly 500 research staff working on a range of research interests from rare anaemias to prostate cancer, and as a result the annual WIMM Day conference always promises to be a stimulating and inspiring ...

News Archive



Postdoctoral Researcher - DNA Damage Signalling (2 posts)

Posted 22/06/2016

Grade 7: £30,738 - £37,768 p.a. We have an exciting opportunity for a Postdoctoral Researcher to be part of the newly established DNA damage signalling group, headed by Dr Andrew Blackford and funded by Cancer Research UK. You will work on a project aiming to provide new insights into the underlying mechanisms that control DNA repair and will validate an experimental framework that could readily be applied to investigate other biological pathwa ...

Other Vacancies


Scratching the itch: towards a new treatment for eczema


Atopic dermatitis is a common form of eczema that affects millions of people worldwide, and for which there is currently no cure. Characterised by dry skin sometimes over the entire body, and intensely itchy lesions in places such as the knees and elbows, the condition makes life extremely uncomfortable for the many people that suffer from it. Understanding how and why this form of eczema develops is critical to identifying new, more effective treatments for the disease, and new research led by Graham Ogg in the Human Immunology Unit at the WIMM holds the promise to do just that. In this latest blog post, Lauren Howson explains what they found.

WIMM Blog Archive