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The mission of the MRC Weatherall Institute of Molecular Medicine (WIMM) is to undertake internationally competitive research into the processes underlying normal cell and molecular biology and to determine the mechanisms by which these processes are perturbed in inherited and acquired human diseases. It is also our mission to translate this research to improve human health. The WIMM is uniquely placed among biomedical institutes throughout the world in its pioneering vision of combining outstanding clinical research with excellent basic science. The WIMM Faculty currently includes an equal mixture of scientists and clinicians working together and in collaboration with the National Institute of Health Research, the NHS and commercial companies with the aim of improving the diagnosis and treatment of human diseases. The major topics of current research include haematology, immunology, stem cell biology, oncology and inherited human genetic diseases. The Institute benefits from strategic support from the MRC.

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The Institute values communication with members of the broader scientific community and the general public and with the support of the Medical Research Council (MRC) we have commissioned three short videos to explain our mission.


Researchers in the MRC Human Immunology Unit discover immune system’s Trojan horse

Researchers in the MRC Human Immunology Unit discover immune system’s Trojan horse

Posted 04/08/2015

Professor Jan Rehwinkel’s team from the MRC Human Immunology Unit have found that human cells use viruses as Trojan horses, transporting a messenger that encourages the immune system to fight the very virus that carries it. The discovery could have implications for the design of new vaccines. Scientists already knew that when a virus containing or producing DNA enters a cell in the body it is detected by a protein called cGAS. This in turn ...


Annual WIMM fundraiser raises over £1000 for urology cancer research

Annual WIMM fundraiser raises over £1000 for urology cancer research

Posted 10/07/2015

Every year in early summer, a team of dedicated volunteers at the WIMM put together a series of fund-raising activities in aid of a local charity, which is often chosen because the beneficiary has links to staff and students at the Institute. This year, the WIMM decided to support UCARE (Urology Cancer Research and Education), a charity based at the nearby Churchill Hospital in Oxford which aims to improve the treatment and care of patients ...

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Further Vacancies


25 years of LMO2: from bad guy to good guy


Twenty-five years ago the gene that codes for the protein LMO2 was discovered. To mark this anniversary, the lab that made this initial finding, now based in the WIMM, have written a review article to highlight the history, current understanding and continued importance of this remarkable protein in human health and disease. In this blog, Jennifer Chambers, a PhD student in the lab, focuses on some key characteristics of this complex protein.

WIMM Blog Archive