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The mission of the MRC Weatherall Institute of Molecular Medicine (WIMM) is to undertake internationally competitive research into the processes underlying normal cell and molecular biology and to determine the mechanisms by which these processes are perturbed in inherited and acquired human diseases. It is also our mission to translate this research to improve human health. The WIMM is uniquely placed among biomedical institutes throughout the world in its pioneering vision of combining outstanding clinical research with excellent basic science. The WIMM Faculty currently includes an equal mixture of scientists and clinicians working together and in collaboration with the National Institute of Health Research, the NHS and commercial companies with the aim of improving the diagnosis and treatment of human diseases. The major topics of current research include haematology, immunology, stem cell biology, oncology and inherited human genetic diseases. The Institute benefits from strategic support from the MRC.

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The Institute values communication with members of the broader scientific community and the general public and with the support of the Medical Research Council (MRC) we have commissioned three short videos to explain our mission.


Breast Cancer NOW Grant Awarded

Breast Cancer NOW Grant Awarded

Posted 30/06/2015

Adrian Harris has received a grant from the new breast cancer charity, Breast Cancer NOW, which combines the previous breast cancer charities Breakthrough Breast Cancer and Breast Cancer Campaign.  The grant is to examine the function of a long non-coding RNA, NEAT1, induced by hypoxia, which helps assemble the nuclear structure known as a paraspeckle.  This can act as an assembly platform for transcription factors and represents a new mechanism ...


Wellcome Trust Postdoctoral Fellowship awarded

Wellcome Trust Postdoctoral Fellowship awarded

Posted 04/06/2015

Dr Beth Psaila has been awarded a Wellcome Trust Postdoctoral Fellowship. Beth will work with Adam Mead and Irene Roberts on the role of megakaryocytes in myelofibrosis (MF), using single cell profiling to study the molecular mechanisms underlying abnormal megakaryopoiesis in MF and the pathways by which megakaryocytes contribute to bone marrow fibrosis. She will spend the first 2 years of her Fellowship working in David Bodine's lab at the ...

 News Archive



Computational / Bioinformatic Genomic Analyst ref: 119073

Posted 26/06/2015

A full-time position is available until 31 March 2017 in the first instance, for an experienced computational/bioinformatic genomics analyst to be responsible for analysis of complex biological datasets involving next generation sequence data (RNA, DNA, Chip-Seq, ATAC-Seq). Funding has been provided through the Oxford Biomedical Research Centre (BRC). This is an exciting project on the cutting edge of translational genomics and biomedical ...

Further Vacancies


Beyond the double helix


So, DNA. It’s a code; it’s made up of four letters, and it’s essential for life. Scientists worked out the sequence of the entire human genome about a decade ago (that’s all the DNA code in your body) so what else is there to know? A lot, says Barbara Xella – it turns out DNA can form all sorts of 3D structures, and if these odd formations aren’t recognized properly by proteins inside the cell, it can be deadly.

WIMM Blog Archive