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The mission of the MRC Weatherall Institute of Molecular Medicine (WIMM) is to undertake internationally competitive research into the processes underlying normal cell and molecular biology and to determine the mechanisms by which these processes are perturbed in inherited and acquired human diseases. It is also our mission to translate this research to improve human health. The WIMM is uniquely placed among biomedical institutes throughout the world in its pioneering vision of combining outstanding clinical research with excellent basic science. The WIMM Faculty currently includes an equal mixture of scientists and clinicians working together and in collaboration with the National Institute of Health Research, the NHS and commercial companies with the aim of improving the diagnosis and treatment of human diseases. The major topics of current research include haematology, immunology, stem cell biology, oncology and inherited human genetic diseases. The Institute benefits from strategic support from the MRC.

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The Institute values communication with members of the broader scientific community and the general public and with the support of the Medical Research Council (MRC) we have commissioned three short videos to explain our mission.


Single cell focus reveals hidden cancer cells

Posted 16/05/2017
Researchers have found a way to identify rogue cancer cells which survive treatment after the rest of the tumour is destroyed, by using a new technique that enables them to identify and characterise individual cancer cells.


Jan Rehwinkel delivers Lister Institute Prize Lecture

Jan Rehwinkel delivers Lister Institute Prize Lecture

Posted 08/05/2017

Congratulations to Jan Rehwinkel, Principal Investigator in the MRC Human Immunology Unit, who delivered his Lister Institute Research Fellowship Prize Lecture on 3 May. Jan shared his research into nucleotide sensing by the immune system, including new work funded by the Lister Institute to investigate detection of DNA and RNA in the ‘Z confirmation’ in anti-viral responses. We were delighted to welcome representatives from the Lister ...

News Archive



Research Assistant in Functional Analysis of Human Haematopoiesis and Leukaemia Ref:128941

Posted 15/05/2017

We are seeking a motivated and enthusiastic Research Assistant to join the research group of Professor Paresh Vyas http://www.imm.ox.ac.uk/paresh-vyas-2 within the Molecular Haematology Unit at the MRC Weatherall Institute of Molecular Medicine. The group’s research interests focus on the analysis of normal and malignant haemopoietic stem/progenitor populations and single cells. You will manage your own research project closely supervised by ...

Other Vacancies


INTERFERing: the immune responses helping cancer cells resist treatment


Cancer treatments like chemotherapy and radiotherapy generally work by causing damage to the DNA of cancer cells. Unfortunately, cancer cells can become resistant to this DNA damage and therefore resistant to the treatments. Recent collaborative research in the WIMM between labs in the Department of Oncology and the MRC Human Immunology Unit sheds light on this process, revealing new markers of treatment resistance in patients and potential future drug targets. Layal Liverpool explains more.

WIMM Blog Archive