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The mission of the MRC Weatherall Institute of Molecular Medicine (WIMM) is to undertake internationally competitive research into the processes underlying normal cell and molecular biology and to determine the mechanisms by which these processes are perturbed in inherited and acquired human diseases. It is also our mission to translate this research to improve human health. The WIMM is uniquely placed among biomedical institutes throughout the world in its pioneering vision of combining outstanding clinical research with excellent basic science. The WIMM Faculty currently includes an equal mixture of scientists and clinicians working together and in collaboration with the National Institute of Health Research, the NHS and commercial companies with the aim of improving the diagnosis and treatment of human diseases. The major topics of current research include haematology, immunology, stem cell biology, oncology and inherited human genetic diseases. The Institute benefits from strategic support from the MRC.

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The Institute values communication with members of the broader scientific community and the general public and with the support of the Medical Research Council (MRC) we have commissioned three short videos to explain our mission.The slimy jelly that helps us respond to infection


WIMM researchers head to Royal Society Summer Science

WIMM researchers head to Royal Society Summer Science

Posted 04/07/2017

  Researchers from RDM kick off a week-long science extravaganza today at The Royal Society Summer Science Exhibition. The team will be exhibiting a unique blend of genetics and virtual reality on their stand, ‘DNA Origami: How do you fold a genome?’ The team are one of 22 exhibits at the festival – a celebration of science and innovation. They will be taking visitors through the intricate world of DNA folding, using virtual reality and ...


Prof Sir David Weatherall awarded highest title in Queen’s Birthday Honours

Prof Sir David Weatherall awarded highest title in Queen’s Birthday Honours

Posted 19/06/2017

We are delighted to announce that Prof Sir David Weatherall has been awarded a GBE, making him a Knight of the Grand Cross. This is the highest rank in the Order of the British Empire and the honour has only been bestowed 16 times since 2000. Prof Sir Weatherall was recognised for his services for medicine and it is wonderful that his pioneering work and commitment to molecular medicine have been recognised in this way. David Weatherall is a ...

News Archive



Postdoctoral Scientist in Cancer Biology ref:130143

Posted 24/07/2017

Applications are invited to apply for a postdoctoral position to discover and develop inhibitors of oncogenic proteins for cancer treatment. The post is available fixed-term until 31 December 2019, funded by Bloodwise. The aim of the work is to discover inhibitors protein-protein interactions involving multi-protein complexes in cancer and develop delivery methods for drug applications. The focus is on mutant RAS in carcinomas and LMO2 in ...

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Breaking boundaries in our DNA

Each of the cells in your body contains an instruction manual, otherwise known as your DNA, with all the information required to build an entire human being. An important open question in biology is how different cells get directed to the right part of this manual to find the instructions for their specific tasks. A new study, published in in Nature Cell Biology today, by a team of scientists co-led by Doug Higgs and Ben Davies shines light on the underlying structural processes that help the cells work out which part of the manual to read to establish their identity. Marieke Oudelaar, a DPhil student in the Higgs and Hughes labs, who was involved in the work, explains more.

WIMM Blog Archive