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Contact information

Email
anne.bridgeman@imm.ox.ac.uk

Research groups

Rehwinkel Group: Nucleic Acid Sensing

Anne Bridgeman

Senior Research Assistant

Recent publications

Varicella-Zoster virus ORF9 is an antagonist of the DNA sensor cGAS.
Journal article

Hertzog J. et al, (2022), EMBO J, 41
Interferon induction held captive in tumor cells.
Journal article

Bridgeman A. and Rehwinkel J., (2021), Mol Cell, 81, 4109 - 4110
Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses.
Journal article

Tang Q. et al, (2021), Immunity, 54, 1961 - 1975.e5
Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.
Journal article

Chauveau L. et al, (2021), EMBO Rep, 22
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Journal article

Clapes T. et al, (2021), Nat Cell Biol, 23, 704 - 717
The RNA sensor MDA5 detects SARS-CoV-2 infection.
Journal article

Sampaio NG. et al, (2021), Sci Rep, 11
RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death.
Journal article

Schilling M. et al, (2020), Cells, 9
SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP.
Journal article

Davenne T. et al, (2020), Cell Rep, 31
cGAMP loading enhances the immunogenicity of VLP vaccines
Journal article

Chauveau L. et al, (2020)
Deoxyguanosine is a TLR7 agonist.
Journal article

Davenne T. et al, (2020), Eur J Immunol, 50, 56 - 62
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Journal article

Glück S. et al, (2017), Nat Cell Biol, 19, 1061 - 1070
Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.
Journal article

Maelfait J. et al, (2017), EMBO J, 36, 2529 - 2543
Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture.
Journal article

Mayer A. et al, (2017), Methods Mol Biol, 1656, 143 - 152
Vector delivery-dependant effect of human tissue plasminogen activator signal peptide on vaccine induction of T cells
Journal article

Hanke T. et al, (2016), Journal of HIV and AIDS
Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.
Journal article

Maelfait J. et al, (2016), Cell Rep, 16, 1492 - 1501
Viruses transfer the antiviral second messenger cGAMP between cells.
Journal article

Bridgeman A. et al, (2015), Science, 349, 1228 - 1232
Transient IL-10 receptor blockade can enhance CD8(+) T cell responses to a simian adenovirus-vectored HIV-1 conserved region immunogen.
Journal article

Clutton G. et al, (2015), Hum Vaccin Immunother, 11, 1030 - 1035
Characterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c mice.
Journal article

Ondondo B. et al, (2014), Clin Vaccine Immunol, 21, 1565 - 1572
Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.
Journal article

Borthwick N. et al, (2014), Mol Ther, 22, 464 - 475
SAMHD1-dependent retroviral control and escape in mice.
Journal article

Rehwinkel J. et al, (2013), EMBO J, 32, 2454 - 2462
SAMHD1-dependent retroviral control and escape in mice
Journal article

Rehwinkel J. et al, (2013), Retrovirology, 10, P70 - P70
Superior induction of T cell responses to conserved HIV-1 regions by electroporated alphavirus replicon DNA compared to that with conventional plasmid DNA vaccine.
Journal article

Knudsen ML. et al, (2012), J Virol, 86, 4082 - 4090
Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques.
Journal article

Rosario M. et al, (2012), AIDS, 26, 275 - 284
Optimizing HIV-1-specific CD8+ T-cell induction by recombinant BCG in prime-boost regimens with heterologous viral vectors.
Journal article

Hopkins R. et al, (2011), Eur J Immunol, 41, 3542 - 3552
Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges.
Journal article

Im E-J. et al, (2011), PLoS Pathog, 7
Dual neonate vaccine platform against HIV-1 and M. tuberculosis.
Journal article

Hopkins R. et al, (2011), PLoS One, 6

More publications