MRC Human Immunology Unit
Human immunology and the development of treatments against infectious diseases, cancer, allergy and autoimmune disease.
MRC Molecular Haematology Unit
Understanding how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders.
Centre for Computational Biology
Using computational biology to help understand complex biological systems and combat a range of human diseases.
Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression
Knapp DJHF. et al, (2018)
Leimbacher P-A. et al, (2019), Mol Cell
Sezgin E. et al, (2019), Nat Protoc
Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos.
Li L. et al, (2019), Nat Commun, 10
SIMMONS A. et al, Nature
Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing.
Rodriguez-Meira A. et al, (2019), Mol Cell