Recent publications published by researchers at the MRC WIMM.
Congenital myasthenic syndrome: is it time for a name change to genetic myasthenic syndrome?
Ramdas S. et al, (2026), Brain
Menin inhibitors: a 2-in-1 defense versus AML immune evasion.
Chakraverty R., (2026), Blood, 147, 482 - 483
Correction to "DNA-Programmable Protein Degradation: Dynamic Control of Proteolysis-Targeting Chimera Activity via DNA Hybridization and Strand Displacement".
Kashyap D. et al, (2026), JACS Au, 6, 653 - 655
Menin maintains enhancer-promoter interactions in a leukemia-specific manner
Sharlandjieva V. et al, (2026)
Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesity.
Liu D. et al, (2026), Science, 391
Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia.
Ren H. et al, (2026), Blood, 147, 180 - 196
Oxford Classic-Defined EMT Risk Stratification of High-Grade Serous Ovarian Cancer for Guiding Treatment Decisions.
Rai L. et al, (2026), Clin Cancer Res, 32, 188 - 202
Absence of Syndactyly Associated With the Common Apert FGFR2 S252W Mutation: A Clinical Report and Likely Molecular Explanation.
Saad R. et al, (2026), Am J Med Genet A, 200, 215 - 222
Lactation, tissue-resident immunity, and protection against breast cancer.
Little M. et al, (2026), Trends Immunol, 47, 3 - 5
Not Apert Syndrome: A Critique of a Recent Case Report by Pan and Yang.
Wilkie AOM., (2026), Am J Med Genet A, 200, 266 - 269
Spatial fibroblast niches define Crohn's fistulae.
McGregor C. et al, (2026), Nature, 649, 703 - 712
Sideways lipid presentation by the antigen-presenting molecule CD1c.
Cao T-P. et al, (2025), Nat Commun
A genome-wide screen identifies Runx2 as a novel regulator of hematopoietic stem cell expansion and T-cell commitment.
Meaker GA. et al, (2025), Blood, 146, 3188 - 3200
Redefining the topology of the human bone marrow using augmented spatial transcriptomic analysis
Cooper RA. et al, (2025)
A high-resolution atlas of the brain predicts lineage and birth order underlying neuronal identity.
Allen AM. et al, (2025), Cell Genom