Peter McHugh
D.Phil
Professor of Molecular Oncology
The study of DNA damage and repair to understand the causes of cancer and improve its treatment.
Brief Biography
Director, Oncology Laboratories, WIMM
Head, DNA Damage and Repair Group, Department of Oncology and WIMM
Royal Society Research Fellow, UCL, 2001-2002
Post-Doctoral Fellow, UCL, 1997-2001
D.Phil Biochemistry, University of Oxford 1996
BSc (Hons) Biochemistry, UMIST, 1991
Recent publications
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Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.
Preprint
Roddan R. et al, (2025)
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Transcription-coupled repair of crosslinking DNA damage.
Journal article
Roddan R. et al, (2025), DNA Repair (Amst), 152
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The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.
Journal article
Song W. et al, (2025), Nucleic Acids Res, 53
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The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.
Preprint
Song W. et al, (2024)
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Molecular insights into the stimulation of SNM1A nuclease activity by CSB during interstrand crosslink processing.
Preprint
Roddan R. et al, (2024)