MRC WIMM Centre for Computational Biology



All research activities within the MRC Weatherall Institute of Molecular Medicine (e.g. Flow Cytometry, Imaging, Single Cell Biology, Transcriptional and Epigenetic research, Chromosome Conformation Studies, Genetic Screens, Clinical Epidemiology) require considerable computational science to support storage and interpretation of the associated data. The Computational Biology Research Group (CBRG) was established at the WIMM in 2003 and consolidated via MRC strategic awards in 2010 and 2014. Having received an MRC Clinical Research Capabilities and Technologies initiative award in 2015 we have been able to considerably expand this activity in the Institute. Importantly we have now established a purpose-built facility for all computational biology at the WIMM. This accommodates approximately 40 computational scientists in addition to the many computational biologists who are already distributed within the WIMM Laboratories. We have now also incorporated the Computational Genomics Analysis and Training (CGAT) group. In addition we incorporate independent computational research groups to develop their own interests including genome biology (Hughes), quantitative biology of cell fate and tissue dynamics (Morrissey) and integrative computational biology and machine learning (Sahakyan).

All of these activities are brought together in the new MRC WIMM Centre for Computational Biology which also has strong links to all relevant computational groups throughout the University of Oxford.