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Publications

Recent publications published by researchers at the MRC WIMM.

The Power of Mouse Models in the Diagnostic Odyssey of Patients with Rare Congenital Anomalies

Twigg S., (2025), Mammalian Genome

Study protocol for putting the ‘Person’ in the PiCTuRE: an exploratory sequential mixed methods-based design, exploring how precision medicine is implemented and experienced by people living with a primary tumour of the craniospinal axis

Mawhinney G. et al, (2025), BMC Cancer, 25

BCL11B-related disease: a single phenotypic entity?

Vedovato-dos-Santos JH. et al, (2025), European Journal of Human Genetics

Magrolimab plus azacitidine vs physician's choice for untreated TP53-mutated acute myeloid leukemia: the ENHANCE-2 study.

Zeidner JF. et al, (2025), Blood

Identification of new candidate drugs in myelodysplastic syndromes with splicing factor mutations by transcriptional profiling and connectivity map analysis.

Sun T. et al, (2025), Br J Haematol

Author Correction: Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells.

Toghani D. et al, (2025), Nat Aging

Precise engineering of chimeric antigen receptor expression levels defines T cell identity and function

Ramos AS. et al, (2025)

RAB23loss-of-function mutation causes context-dependent ciliopathy in Carpenter syndrome

Leong WY. et al, (2025)

Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco).

Potel CM. et al, (2025), Nat Struct Mol Biol

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline.

Yang X. et al, (2025), Adv Healthc Mater

Anatomy of the diaphragmatic crura and other paraspinal structures relevant to en-bloc spondylectomy for lumbar spine tumours.

Khadanovich A. et al, (2025), Eur Spine J

Elevated reactive oxygen species can drive the alternative lengthening of telomeres pathway in ATRX-null cancers.

Goncalves T. et al, (2025), Nucleic Acids Res, 53

Elevated reactive oxygen species can drive the alternative lengthening of telomeres pathway in ATRX-null cancers.

Goncalves T. et al, (2025), Nucleic Acids Res, 53

Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms.

Sivakumar S. et al, (2025), Nat Commun, 16

Going nuclear: Improved antisense oligonucleotide activity through conjugation with a nuclear importer

Kashyap D. et al, (2025)

MAIT cells protect against sterile lung injury.

Zhang X. et al, (2025), Cell Rep, 44

Spatiotemporal dynamics of fetal liver hematopoietic niches.

Mesquita Peixoto M. et al, (2025), J Exp Med, 222

Idiopathic pulmonary fibrosis in the UK: findings from the British Thoracic Society UK Idiopathic Pulmonary Fibrosis Registry

Fahim A. et al, (2025), BMJ Open Respiratory Research, 12, e002773 - e002773

mTOR-mediated p62/SQSTM1 stabilization confers a robust survival mechanism for ovarian cancer

Tamura T. et al, (2025), Cancer Letters, 217565 - 217565

Preservation of a youthful path to evergreen platelets?

Jacobsen SEW., (2025), Cell Res, 35, 93 - 94

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