Recent publications published by researchers at the MRC WIMM.
Incidence of symptomatic, image-confirmed venous thromboembolism following hospitalization for COVID-19 with 90-day follow-up.
Journal article
Salisbury R. et al, (2020), Blood Adv, 4, 6230 - 6239
Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.
Journal article
Labuhn M. et al, (2019), Cancer Cell, 36, 123 - 138.e10
Variation in PU.1 binding and chromatin looping at neutrophil enhancers influences autoimmune disease susceptibility
Journal article
Watt S. et al, (2019)
GARFIELD classifies disease-relevant genomic features through integration of functional annotations with association signals.
Journal article
Iotchkova V. et al, (2019), Nat Genet, 51, 343 - 353
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume.
Journal article
Haworth S. et al, (2019), Nat Commun, 10
Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.
Journal article
Iotchkova V. et al, (2018), Nat Genet, 50
Low frequency genetic variation in the TP53 locus has large effects on head circumference and intracranial volume
Conference paper
St Pourcain B. et al, (2018), BEHAVIOR GENETICS, 48, 514 - 515
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
Journal article
Astle WJ. et al, (2016), Cell, 167, 1415 - 1429.e19
GARFIELD - GWAS Analysis of Regulatory or Functional Information Enrichment with LD correction
Journal article
Iotchkova V. et al, (2016)
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.
Journal article
Iotchkova V. et al, (2016), Nature genetics
Significant impact of miRNA-target gene networks on genetics of human complex traits.
Journal article
Okada Y. et al, (2016), Sci Rep, 6
The UK10K project identifies rare variants in health and disease.
Journal article
UK10K Consortium None. et al, (2015), Nature, 526, 82 - 90
MultiMeta: an R package for meta-analyzing multi-phenotype genome-wide association studies.
Journal article
Vuckovic D. et al, (2015), Bioinformatics, 31, 2754 - 2756
Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.
Journal article
Timpson NJ. et al, (2015), Nat Commun, 6
Whole-genome sequence-based analysis of thyroid function.
Journal article
Taylor PN. et al, (2015), Nat Commun, 6
FORGE: A tool to discover cell specific enrichments of GWAS associated SNPs in regulatory regions
Journal article
Dunham I. et al, (2015)
MultiMeta: An R Package for Meta-Analyzing Multi-Phenotype Genome-Wide Association Studies
Conference paper
Vuckovic D. et al, (2015), HUMAN HEREDITY, 79, 48 - 48
A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.
Journal article
Timpson NJ. et al, (2014), Nat Commun, 5
A multiple phenotype imputation method for genetic studies
Journal article
Marchini J. and Dahl A., Nature Genetics
eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data.
Journal article
Breeze CE. et al, Cell Rep, 17, 2137 - 2150