Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Publications

Recent publications published by researchers at the MRC WIMM.

Addendum: Precise tuning of gene expression levels in mammalian cells.

Michaels YS. et al, (2019), Nat Commun, 10

Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression.

Knapp DJHF. et al, (2019), Nat Commun, 10

Precise tuning of gene expression levels in mammalian cells.

Michaels YS. et al, (2019), Nat Commun, 10

CRISPR-Cas9 targeting of MMP13 in human chondrocytes leads to significantly reduced levels of the metalloproteinase and enhanced type II collagen accumulation.

Seidl CI. et al, (2019), Osteoarthritis Cartilage, 27, 140 - 147

MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila.

Goodwin PR. et al, (2018), Cell Rep, 23, 3776 - 3786

Precise tuning of gene expression output levels in mammalian cells

Michaels Y. et al, (2018)

Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression

Knapp DJHF. et al, (2018)

The Drosophila homologue of MEGF8 is essential for early development.

Lloyd DL. et al, (2018), Sci Rep, 8

Regulation of Circadian Behavior by Astroglial MicroRNAs in Drosophila.

You S. et al, (2018), Genetics, 208, 1195 - 1207

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.

Wu Q. et al, (2017), Nat Commun, 8

A multiplexable TALE-based binary expression system for in vivo cellular interaction studies.

Toegel M. et al, (2017), Nat Commun, 8

Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors.

Baeumler TA. et al, (2017), Cell Rep, 20, 2639 - 2653

Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development.

Phillips TJ. et al, (2017), Sci Rep, 7

Identification of Usp8 as a toxicity modifying Deubiquitinase for alpha-synuclein

Alexopoulou Z. et al, (2017), EUROPEAN JOURNAL OF NEUROLOGY, 24, 766 - 766

Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs.

Ferry QRV. et al, (2017), Nat Commun, 8

Interrogation of Functional miRNA-Target Interactions by CRISPR/Cas9 Genome Engineering.

Michaels YS. et al, (2017), Methods Mol Biol, 1580, 79 - 97

Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease.

Alexopoulou Z. et al, (2016), Proc Natl Acad Sci U S A, 113, E4688 - E4697

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.

Reilly SN. et al, (2016), Sci Transl Med, 8

Tiny giants of gene regulation: experimental strategies for microRNA functional studies.

Steinkraus BR. et al, (2016), Wiley Interdiscip Rev Dev Biol, 5, 311 - 362

The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184.

Sharifkhodaei Z. et al, (2016), J Cell Sci, 129, 1477 - 1489

Load More

Include forthcoming?