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Publications

Recent publications published by researchers at the MRC WIMM.

A locally administered single-cycle influenza vaccine expressing a non-fusogenic stabilized hemagglutinin stimulates strong T-cell and neutralizing antibody immunity.

Sadler HL. et al, (2025), J Virol

The molecular reach of antibodies crucially underpins their viral neutralisation capacity.

Huhn A. et al, (2025), Nat Commun, 16

Development of a recombinant non-replicating Newcastle disease virus.

Cheow P-S. et al, (2024), Avian Pathol, 1 - 9

Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses.

Hills RA. et al, (2024), Nat Nanotechnol

Single-cycle influenza virus vaccine generates lung CD8+ Trm that cross-react against viral variants and subvert virus escape mutants.

Zheng MZM. et al, (2023), Sci Adv, 9

The molecular reach of antibodies determines their SARS-CoV-2 neutralisation potency

Huhn A. et al, (2023)

Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents.

Gelinas AD. et al, (2023), Mol Ther Nucleic Acids, 31, 370 - 382

Multiviral Quartet Nanocages Elicit Broad Anti-Coronavirus Responses for Proactive Vaccinology.

Hills RA. et al, (2023), bioRxiv

Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.

Huang K-YA. et al, (2023), Nat Commun, 14

Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors.

Kandasamy M. et al, (2023), Elife, 12

The magnitude and cross reactivity of SARS-CoV-2 specific antibody responses in vaccinated and unvaccinated Sri Lankan children and association with nutrition status

Jeewandara C. et al, (2023)

Cutting Edge: High-Dose Live Attenuated Influenza Vaccines Elicit Pulmonary Tissue-Resident Memory CD8+ T Cells in the Face of Pre-Existing Humoral Immunity.

Zheng MZM. et al, (2022), J Immunol, 209, 1832 - 1836

Cutting Edge: High-Dose Live Attenuated Influenza Vaccines Elicit Pulmonary Tissue-Resident Memory CD8+ T Cells in the Face of Pre-Existing Humoral Immunity.

Zheng MZM. et al, (2022), J Immunol

Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models.

Cohen AA. et al, (2022), Science, 377

Pathogen-sugar interactions revealed by universal saturation transfer analysis.

Buchanan CJ. et al, (2022), Science, 377

SpySwitch enables pH- or heat-responsive capture and release for plug-and-display nanoassembly.

Vester SK. et al, (2022), Nat Commun, 13

Immune responses to Sinopharm/BBIBP-CorV in individuals in Sri Lanka.

Jeewandara C. et al, (2022), Immunology

Kinetics of immune responses to SARS-CoV-2 proteins in individuals with varying severity of infection and following a single dose of the AZD1222.

Jayathilaka D. et al, (2022), Clin Exp Immunol, 208, 323 - 331

Persistence of immune responses to the Sinopharm/BBIBP-CorV vaccine.

Jeewandara C. et al, (2022), Immun Inflamm Dis, 10

Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites.

MacLean AJ. et al, (2022), Immunity, 55, 718 - 733.e8

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