Recent publications published by researchers at the MRC WIMM.
The molecular reach of antibodies crucially underpins their viral neutralisation capacity.
Huhn A. et al, (2025), Nat Commun, 16
Development of a recombinant non-replicating Newcastle disease virus.
Cheow P-S. et al, (2024), Avian Pathol, 1 - 9
Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses.
Hills RA. et al, (2024), Nat Nanotechnol
Single-cycle influenza virus vaccine generates lung CD8+ Trm that cross-react against viral variants and subvert virus escape mutants.
Zheng MZM. et al, (2023), Sci Adv, 9
The molecular reach of antibodies determines their SARS-CoV-2 neutralisation potency
Huhn A. et al, (2023)
Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents.
Gelinas AD. et al, (2023), Mol Ther Nucleic Acids, 31, 370 - 382
Multiviral Quartet Nanocages Elicit Broad Anti-Coronavirus Responses for Proactive Vaccinology.
Hills RA. et al, (2023), bioRxiv
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.
Huang K-YA. et al, (2023), Nat Commun, 14
Cutting Edge: High-Dose Live Attenuated Influenza Vaccines Elicit Pulmonary Tissue-Resident Memory CD8+ T Cells in the Face of Pre-Existing Humoral Immunity.
Zheng MZM. et al, (2022), J Immunol, 209, 1832 - 1836
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models.
Cohen AA. et al, (2022), Science, 377
Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Buchanan CJ. et al, (2022), Science, 377
SpySwitch enables pH- or heat-responsive capture and release for plug-and-display nanoassembly.
Vester SK. et al, (2022), Nat Commun, 13
Immune responses to Sinopharm/BBIBP-CorV in individuals in Sri Lanka.
Jeewandara C. et al, (2022), Immunology
Kinetics of immune responses to SARS-CoV-2 proteins in individuals with varying severity of infection and following a single dose of the AZD1222.
Jayathilaka D. et al, (2022), Clin Exp Immunol, 208, 323 - 331
Persistence of immune responses to the Sinopharm/BBIBP-CorV vaccine.
Jeewandara C. et al, (2022), Immun Inflamm Dis, 10
Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites.
MacLean AJ. et al, (2022), Immunity, 55, 718 - 733.e8