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Publications

Recent publications published by researchers at the MRC WIMM.

Specific Modulation of CRISPR Transcriptional Activators through RNA-Sensing Guide RNAs in Mammalian Cells and Zebrafish Embryos

Pelea O. et al, (2023)

Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors

Williams R. et al, (2022)

RNA-Responsive gRNAs for Controlling CRISPR Activity: Current Advances, Future Directions, and Potential Applications

Pelea O. et al, (2022), The CRISPR Journal

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.

Baranasic D. et al, (2022), Nat Genet

A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy.

Rajakumar T. et al, (2022), NPJ Precis Oncol, 6

Single-cell atlas of early chick development reveals gradual segregation of neural crest lineage from the neural plate border during neurulation

Williams RM. et al, (2022), eLife, 11

Evidence from oyster suggests an ancient role for Pdx in regulating insulin gene expression in animals

Xu F. et al, (2021), Nature Communications, 12

Segregation of neural crest specific lineage trajectories from a heterogeneous neural plate border territory only emerges at neurulation

Williams R. et al, (2021)

Distinct epicardial gene regulatory programmes drive development and regeneration of the zebrafish heart

Weinberger M. et al, (2021)

Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells.

Artibani M. et al, (2021), JCI Insight

Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension.

Mok GF. et al, (2021), Nat Commun, 12

Neuromesodermal progenitor origin of trunk neural crest in vivo

Lukoseviciute M. et al, (2021)

Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach.

Perera SN. et al, (2020), Glia

An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells.

Miyata M. et al, (2020), Blood, 136, 269 - 278

A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes.

KaramiNejadRanjbar M. et al, (2020), Elife, 9

Functional Heterogeneity within the Developing Zebrafish Epicardium.

Weinberger M. et al, (2020), Dev Cell, 52, 574 - 590.e6

The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells.

Hu Z. et al, (2020), Cancer Cell, 37, 226 - 242.e7

Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair.

Simões FC. et al, (2020), Nat Commun, 11

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages.

Ling ITC. and Sauka-Spengler T., (2019), Nat Cell Biol, 21, 1504 - 1517

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo.

Williams RM. et al, (2019), Dev Cell, 51, 255 - 276.e7

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