Recent publications published by researchers at the MRC WIMM.
Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction.
Sayers JR. et al, (2025), Nat Cardiovasc Res
Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors.
Williams RM. et al, (2024), PLoS Biol, 22
Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish.
Chong-Morrison V. et al, (2023), Biol Open, 12
RNA-Responsive gRNAs for Controlling CRISPR Activity: Current Advances, Future Directions, and Potential Applications
Pelea O. et al, (2022), The CRISPR Journal
Cellular plasticity in the neural crest and cancer.
Hu Z. and Sauka-Spengler T., (2022), Curr Opin Genet Dev, 75
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic D. et al, (2022), Nat Genet, 54, 1037 - 1050
A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy.
Rajakumar T. et al, (2022), NPJ Precis Oncol, 6
Single-cell atlas of early chick development reveals gradual segregation of neural crest lineage from the neural plate border during neurulation
Williams RM. et al, (2022), eLife, 11
Evidence from oyster suggests an ancient role for Pdx in regulating insulin gene expression in animals
Xu F. et al, (2021), Nature Communications, 12
Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells.
Artibani M. et al, (2021), JCI Insight
Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension.
Mok GF. et al, (2021), Nat Commun, 12