Recent publications published by researchers at the MRC WIMM.
Immunogenicity of MVA-BN vaccine deployed as mpox prophylaxis: a prospective cohort study and analysis of transcriptomic predictors of response
Drennan P. et al, (2024), The Lancet Microbe
Cognitive and psychiatric symptom trajectories 2-3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK.
Taquet M. et al, (2024), Lancet Psychiatry
Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study - PHOSP-COVID.
Elneima O. et al, (2024), ERJ Open Res, 10
Long COVID and cardiovascular disease: a prospective cohort study.
Lawson CA. et al, (2024), Open Heart, 11
Transient synaptic CD61 pairing with CD103 increases the cytotoxicity of antigen-specific T cells.
(2024), Nature immunology, 25, 739 - 740
Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia.
Liang Z. et al, (2024), Cell Rep, 43
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Liew F. et al, (2024), Nat Immunol, 25, 607 - 621
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
Hamid MHBA. et al, (2024), Nat Immunol
Accelarated immune ageing is associated with COVID-19 disease severity.
Lord JM. et al, (2024), Immun Ageing, 21
Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study
(2023), International journal of epidemiology, 53
Durability and cross-reactive immune memory to SARS-CoV-2 in individuals 2 years after recovery from COVID-19: a longitudinal cohort study.
Guo L. et al, (2023), Lancet Microbe
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.
Weeratunga P. et al, (2023), Nat Commun, 14
Probing long COVID through a proteomic lens: a comprehensive two-year longitudinal cohort study of hospitalised survivors.
Gu X. et al, (2023), EBioMedicine, 98
Long COVID research: an update from the PHOSP-COVID Scientific Summit.
Brightling CE. et al, (2023), Lancet Respir Med, 11, e93 - e94
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.
C-MORE/PHOSP-COVID Collaborative Group None., (2023), Lancet Respir Med, 11, 1003 - 1019
SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses.
Wellington D. et al, (2023), Heliyon, 9
Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2.
Antoun E. et al, (2023), Nat Immunol, 24, 1594 - 1596
Engineering immunosuppressive drug-resistant armored (IDRA) SARS-CoV-2 T cells for cell therapy.
Chen Q. et al, (2023), Cell Mol Immunol
Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history.
Hornsby H. et al, (2023), Nat Commun, 14
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination.
Yin Z. et al, (2023), Cell Rep, 42