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Publications

Recent publications published by researchers at the MRC WIMM.

Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts.

Moura PL. et al, (2024), Cancer Res, 84, 211 - 225

Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation.

Tobiasson M. et al, (2024), Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.

Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632

Absolute risk estimation of new-onset proteinuria in patients with systemic lupus erythematosus: a Danish nationwide cohort study.

Andersen M. et al, (2023), Clin Exp Rheumatol, 41, 2264 - 2268

Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts.

Todisco G. et al, (2023), Clin Cancer Res, 29, 4256 - 4267

Myocardial fibrosis associates with lupus anticoagulant in patients with systemic lupus erythematosus.

Myhr KA. et al, (2023), Int J Cardiovasc Imaging

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo.

Giannakopoulou E. et al, (2023), Nat Cancer

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.

Luis TC. et al, (2023), Nat Commun, 14

Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells.

Belander Strålin K. et al, (2023), Cell Res

Global comment on the use of hydroxychloroquine during the periconception period and pregnancy in women with autoimmune diseases

Schreiber K. et al, (2023), The Lancet Rheumatology, 5, e501 - e506

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.

Luis TC. et al, (2023), Nature communications, 14

Risk of End-Stage Renal Disease in Patients With Systemic Lupus Erythematosus and Diabetes Mellitus: A Danish Nationwide Cohort Study.

Hansen RB. et al, (2023), Arthritis Care Res (Hoboken), 75, 1871 - 1877

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.

Rodriguez-Meira A. et al, (2023), Nat Genet, 55, 1531 - 1541

Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.

Borsa M. et al, (2023), Autophagy, 1 - 13

Systemically produced Kit ligand is sufficient to maintain mouse hematopoietic stem cells

NERLOV C. et al, (2023), Blood

Association Between Severe Nonadherence to Hydroxychloroquine and Systemic Lupus Erythematosus Flares, Damage, and Mortality in 660 Patients From the SLICC Inception Cohort.

Nguyen Y. et al, (2023), Arthritis Rheumatol

Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.

Wojtowicz EE. et al, (2023), Genome Biol, 24

Epigenetic programming defines haematopoietic stem cell fate restriction.

Meng Y. et al, (2023), Nat Cell Biol, 25, 812 - 822

Effect of a 12-week high-intensity exercise intervention: a comparison of cardiac exercise adaptations during biological disease-modifying antirheumatic drug treatment (TNF inhibitors vs IL-6 signalling inhibitors) in patients with rheumatoid arthritis - study protocol for a randomised controlled trial.

Jønck S. et al, (2023), BMJ open, 13

Machine learning identifies clusters of longitudinal autoantibody profiles predictive of systemic lupus erythematosus disease outcomes.

Choi MY. et al, (2023), Ann Rheum Dis

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