Recent publications published by researchers at the MRC WIMM.
Preservation of a youthful path to evergreen platelets?
Jacobsen SEW., (2025), Cell Res, 35, 93 - 94
Germline UBA1 Variant With Somatic Amplification in a Woman With Inflammatory Diseases and Myelodysplastic Syndrome.
Creignou M. et al, (2025), Ann Intern Med
Rejuvenating immunity through a balancing stem cell act.
Jacobsen SEW., (2024), Cell Res, 34, 826 - 827
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells.
Carrelha J. et al, (2024), Nat Immunol, 25, 1007 - 1019
Identification and surveillance of rare relapse-initiating stem cells during complete remission after transplantation.
Dimitriou M. et al, (2024), Blood, 143, 953 - 966
Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts.
Moura PL. et al, (2024), Cancer Res, 84, 211 - 225
Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation.
Tobiasson M. et al, (2024), Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.
Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632
Absolute risk estimation of new-onset proteinuria in patients with systemic lupus erythematosus: a Danish nationwide cohort study.
Andersen M. et al, (2023), Clin Exp Rheumatol, 41, 2264 - 2268
Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts.
Todisco G. et al, (2023), Clin Cancer Res, 29, 4256 - 4267
Myocardial fibrosis associates with lupus anticoagulant in patients with systemic lupus erythematosus.
Myhr KA. et al, (2023), Int J Cardiovasc Imaging
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo.
Giannakopoulou E. et al, (2023), Nat Cancer
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Luis TC. et al, (2023), Nat Commun, 14
Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells.
Belander Strålin K. et al, (2023), Cell Res
Global comment on the use of hydroxychloroquine during the periconception period and pregnancy in women with autoimmune diseases
Schreiber K. et al, (2023), The Lancet Rheumatology, 5, e501 - e506
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Luis TC. et al, (2023), Nature communications, 14
Risk of End-Stage Renal Disease in Patients With Systemic Lupus Erythematosus and Diabetes Mellitus: A Danish Nationwide Cohort Study.
Hansen RB. et al, (2023), Arthritis Care Res (Hoboken), 75, 1871 - 1877
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.
Rodriguez-Meira A. et al, (2023), Nat Genet, 55, 1531 - 1541
Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa M. et al, (2023), Autophagy, 1 - 13
Systemically produced Kit ligand is sufficient to maintain mouse hematopoietic stem cells
NERLOV C. et al, (2023), Blood