Recent publications published by researchers at the MRC WIMM.
Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability.
Journal article
Hodson C. et al, (2022), Proc Natl Acad Sci U S A, 119
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks.
Journal article
Shorrocks A-MK. et al, (2021), Nat Commun, 12
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Journal article
Leimbacher P-A. et al, (2019), Mol Cell, 74, 571 - 583.e8
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.
Journal article
Holme H. et al, (2018), Scientific reports, 8
ATR Is a Therapeutic Target in Synovial Sarcoma
Journal article
Jones SE. et al, (2017), Cancer Research, 77, 7014 - 7026
ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A
Journal article
Williamson CT. et al, (2016), Nature Communications, 7