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Recent publications published by researchers at the MRC WIMM.

An ontogenetic switch drives the positive and negative selection of B cells.

Journal article

Xu X. et al, (2020), Proc Natl Acad Sci U S A, 117, 3718 - 3727

An essential role for the Zn2+ transporter ZIP7 in B cell development.

Journal article

Anzilotti C. et al, (2019), Nat Immunol, 20, 350 - 361

53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.

Journal article

Ghezraoui H. et al, (2018), Nature, 560, 122 - 127

Capturing resting T cells: the perils of PLL.

Journal article

Santos AM. et al, (2018), Nat Immunol, 19, 203 - 205

B1a B cells require autophagy for metabolic homeostasis and self-renewal.

Journal article

Clarke AJ. et al, (2018), J Exp Med, 215, 399 - 413

Immune Checkpoints as Therapeutic Targets in Autoimmunity.

Journal article

Paluch C. et al, (2018), Front Immunol, 9

NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.

Journal article

Schwerd T. et al, (2017), Mucosal immunology

THEMIS: Two Models, Different Thresholds.

Journal article

Choi S. et al, (2017), Trends Immunol, 38, 622 - 632

Themis2: setting the threshold for B-cell selection.

Journal article

Deobagkar-Lele M. et al, (2017), Cellular and Molecular Immunology, 14, 643 - 645

A dominant-negative mutation in TNFR1 results in increased susceptibility to pulmonary tuberculosis infection


Saunders BM. et al, (2016), EUROPEAN JOURNAL OF IMMUNOLOGY, 46, 765 - 765

Complex Genetic Control of Autoimmune Disease


Bull K. and Cornall R., (2016), Encyclopedia of Immunobiology, 5, 133 - 141

Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection.

Journal article

Siggs OM. et al, (2015), Proc Natl Acad Sci U S A, 112, E5706 - E5714

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.

Journal article

Taylor JC. et al, (2015), Nat Genet, 47, 717 - 726

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.

Journal article

Zhang Q. et al, (2014), J Exp Med, 211, 2549 - 2566

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

Journal article

Zhang Q. et al, (2014), JOURNAL OF EXPERIMENTAL MEDICINE, 211, 2549 - 2566

DOCK8 Regulates Lymphocyte Shape Integrity for Skin Antiviral Immunity

Conference paper

Su H. et al, (2014), JOURNAL OF CLINICAL IMMUNOLOGY, 34, S471 - S472

Erythrocytosis associated with a novel missense mutation in the BPGM gene.

Journal article

Petousi N. et al, (2014), Haematologica, 99, e201 - e204

Genetic analysis of autoimmune type 1 diabetes mellitus in mice (Reprinted from Nature, vol 351, pg 542-547, 1991)

Journal article

Todd JA. et al, (2014), JOURNAL OF IMMUNOLOGY, 193, 7 - 12

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