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Publications

Recent publications published by researchers at the MRC WIMM.

B cells require DOCK8 to elicit and integrate T cell help when antigen is limiting

Deobagkar-Lele M. et al, (2024), Science Immunology, 9

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

Lippert AH. et al, (2024), Immunity, 57, 256 - 270.e10

Tissue-resident memory T cells in pancreatic ductal adenocarcinoma co-express PD-1 and TIGIT and functional inhibition is reversible by dual antibody blockade.

Pearce H. et al, (2023), Cancer Immunol Res

Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-Like Autoimmunity.

Hodgson R. et al, (2023), J Immunol

NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance.

Hodgson R. et al, (2022), Commun Biol, 5

Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison.

National SARS-CoV-2 Serology Assay Evaluation Group None., (2020), Lancet Infect Dis, 20, 1390 - 1400

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.

Peng Y. et al, (2020), Nat Immunol, 21, 1336 - 1345

SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020.

Lumley SF. et al, (2020), Euro Surveill, 25

Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development.

Burrows N. et al, (2020), Nat Immunol

Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study.

Eyre DW. et al, (2020), Elife, 9

Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel

Adams E. et al, (2020)

Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.

Peng Y. et al, (2020), bioRxiv

An ontogenetic switch drives the positive and negative selection of B cells.

Xu X. et al, (2020), Proc Natl Acad Sci U S A, 117, 3718 - 3727

Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel.

Adams ER. et al, (2020), Wellcome open research, 5

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

Abeler-Dörner L. et al, (2020), Nat Immunol, 21, 86 - 100

Treatment With FoxP3+ Antigen-Experienced T Regulatory Cells Arrests Progressive Retinal Damage in a Spontaneous Model of Uveitis.

Liu Y-H. et al, (2020), Front Immunol, 11

An essential role for the Zn2+ transporter ZIP7 in B cell development.

Anzilotti C. et al, (2019), Nat Immunol, 20, 350 - 361

53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.

Ghezraoui H. et al, (2018), Nature, 560, 122 - 127

Partial retinal photoreceptor loss in a transgenic mouse model associated with reduced levels of interphotoreceptor retinol binding protein (IRBP, RBP3).

Liu Y-H. et al, (2018), Exp Eye Res, 172, 54 - 65

Capturing resting T cells: the perils of PLL.

Santos AM. et al, (2018), Nat Immunol, 19, 203 - 205

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