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Recent publications published by researchers at the MRC WIMM.

Neuronal enhancers are hotspots for DNA single-strand break repair.

Journal article

Wu W. et al, (2021), Nature

Repeat expansions confer WRN dependence in microsatellite-unstable cancers.

Journal article

van Wietmarschen N. et al, (2020), Nature, 586, 292 - 298

The SNM1A DNA repair nuclease.

Journal article

Baddock HT. et al, (2020), DNA Repair (Amst), 95

Genetic and functional insights into CDA-I prevalence and pathogenesis.

Journal article

Olijnik A-A. et al, (2020), J Med Genet

XPF-ERCC1: Linchpin of DNA crosslink repair.

Journal article

McHugh PJ., (2020), PLoS Genet, 16

Optimised oligonucleotide substrates to assay XPF-ERCC1 nuclease activity for the discovery of DNA repair inhibitors.

Journal article

Thomas AM. et al, (2019), Chem Commun (Camb), 55, 11671 - 11674

A hydroxamic-acid-containing nucleoside inhibits DNA repair nuclease SNM1A.

Journal article

Doherty W. et al, (2019), Org Biomol Chem, 17, 8094 - 8105

Microhomologies are prevalent at Cas9-induced larger deletions.

Journal article

Owens DDG. et al, (2019), Nucleic Acids Res, 47, 7402 - 7417

Antiviral activity of bone morphogenetic proteins and activins.

Journal article

Eddowes LA. et al, (2019), Nat Microbiol, 4, 339 - 351

Squaramide-Based 5'-Phosphate Replacements Bind to the DNA Repair Exonuclease SNM1A.

Journal article

Dürr E-M. et al, (2018), ChemistrySelect, 3, 12824 - 12829

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