Recent publications published by researchers at the MRC WIMM.
Microtubule poleward flux as a target for modifying chromosome segregation errors
Risteski P. et al, (2024), Proceedings of the National Academy of Sciences, 121
Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin
Sacristan C. et al, (2024), Cell
New characterization and safety evaluation of human limbal stem cells used in clinical application: fidelity of mitotic process and mitotic spindle morphologies
Zekušić M. et al, (2023), Stem Cell Research & Therapy, 14
The TRIM69-MST2 signaling axis regulates centrosome dynamics and chromosome segregation.
Wang Y. et al, (2023), Nucleic acids research, 51, 10568 - 10589
Permeable dye-based fluorescent speckle microscopy for human cells.
Risteski P., (2023), Nat Rev Mol Cell Biol, 24
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment.
Risteski P. et al, (2022), Cell Rep, 40
Nuclear chromosome locations dictate segregation error frequencies.
Klaasen SJ. et al, (2022), Nature, 607, 604 - 609
Biomechanics of chromosome alignment at the spindle midplane.
Risteski P. et al, (2021), Curr Biol, 31, R574 - R585
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation.
Vukušić K. et al, (2021), Dev Cell, 56, 1253 - 1267.e10
Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces.
Jagrić M. et al, (2021), Elife, 10
PRC1-labeled microtubule bundles and kinetochore pairs show one-to-one association in metaphase.
Polak B. et al, (2017), EMBO Rep, 18, 217 - 230
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores.
Kajtez J. et al, (2016), Nat Commun, 7