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Publications

Recent publications published by researchers at the MRC WIMM.

Magrolimab in Combination With Azacitidine in Patients With Higher-Risk Myelodysplastic Syndromes: Final Results of a Phase Ib Study.

Sallman DA. et al, (2023), J Clin Oncol

Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.

Jiao W. et al, (2022), Nature communications, 13

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower.

Shuai S. et al, (2022), Nature communications, 13

Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours.

Bhandari V. et al, (2022), Nature communications, 13

Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer.

Sieverling L. et al, (2022), Nature communications, 13

Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.

Zhang Y. et al, (2022), Nature communications, 13

Author Correction: Inferring structural variant cancer cell fraction.

Cmero M. et al, (2022), Nature communications, 13

Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes.

Reyna MA. et al, (2022), Nature communications, 13

Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma.

Gooding S. et al, (2022), Blood, 140, 1816 - 1821

TP53-Mutated Myelodysplastic Syndrome and Acute Myeloid Leukemia: Biology, Current Therapy, and Future Directions

Daver NG. et al, (2022), Cancer Discovery, OF1 - OF14

A Phase 3, Randomized Trial of Magrolimab in Combination With Venetoclax and Azacitidine in Previously Untreated Patients With Acute Myeloid Leukemia Ineligible for Intensive Chemotherapy (ENHANCE-3)

Daver N. et al, (2022), AMERICAN JOURNAL OF HEMATOLOGY, 97, S5 - S5

A Phase 3, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination With Azacitidine in Previously Untreated Patients With TP53-Mutant Acute Myeloid Leukemia

Daver N. et al, (2022), AMERICAN JOURNAL OF HEMATOLOGY, 97, S5 - S6

AML-262 Pivekimab Sunirine (PVEK, IMGN632) Triplet With Azacitidine and Venetoclax Shows Broad Activity in Adverse Genetic Subsets of Relapsed/Refractory Acute Myeloid Leukemia and Reduced Infusion-Related Reactions

Daver N. et al, (2022), Clinical Lymphoma, Myeloma and Leukemia, 22, S231 - S232

AML-348 A Phase Ib/II Study of Ivosidenib With Venetoclax +/- Azacitidine in IDH1-Mutated Hematologic Malignancies

Lachowiez C. et al, (2022), Clinical Lymphoma, Myeloma and Leukemia, 22, S240 - S241

AML-399 A Phase 2, Open-Label, Multiarm, Multicenter Study to Evaluate Magrolimab Combined With Antileukemia Therapies for First-Line, Relapsed/Refractory, or Maintenance Treatment of Acute Myeloid Leukemia (AML)

Vyas P. et al, (2022), Clinical Lymphoma, Myeloma and Leukemia, 22

AML-432 Overall Survival (OS) by IDH2 Mutant Allele (R140 or R172) in Patients With Late-Stage, Mutant-IDH2 Relapsed/Refractory Acute Myeloid Leukemia (AML) Treated With Enasidenib or Conventional Care Regimens (CCR) in the Randomized, Open-Label, Phase 3 IDHENTIFY Trial

DiNardo CD. et al, (2022), Clinical Lymphoma, Myeloma and Leukemia, 22, S249 - S250

AML-464 Tolerability and Efficacy of the First-In-Class Anti-CD47 Antibody Magrolimab Combined With Azacitidine in Frontline Patients With TP53-Mutated Acute Myeloid Leukemia (AML): Phase 1b Results

Daver N. et al, (2022), Clinical Lymphoma, Myeloma and Leukemia, 22, S253 - S254

Magrolimab in Combination With Azacitidine for Patients With Untreated Higher-Risk Myelodysplastic Syndromes: 5F9005 Phase 1b Study Results

Sallman DA. et al, (2022), AMERICAN JOURNAL OF HEMATOLOGY, 97, S20 - S21

MDS-445 Magrolimab In Combination With Azacitidine for Patients With Untreated Higher-Risk Myelodysplastic Syndromes (HR MDS): 5F9005 Phase 1b Study Results

Sallman D. et al, (2022), Clinical Lymphoma, Myeloma and Leukemia, 22, S314 - S315

MDS-482 Impact Of Magrolimab in Combination With Azacitidine on Red Blood Cells (RBCs) in Patients With Higher-Risk Myelodysplastic Syndromes (HR MDS)

Chen J. et al, (2022), Clinical Lymphoma, Myeloma and Leukemia, 22, S317 - S318

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