Recent publications published by researchers at the MRC WIMM.
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center
Grootveld AK. et al, (2023), Cell
Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites.
MacLean AJ. et al, (2022), Immunity, 55, 718 - 733.e8
Competition for refueling rather than cyclic reentry initiation evident in germinal centers.
Long Z. et al, (2022), Sci Immunol, 7
Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection.
Frost JN. et al, (2021), Med (N Y), 2, 164 - 179.e12
Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging.
Stewart I. et al, (2018), Immunity, 49, 477 - 489.e7
Expression of the Plasma Cell Transcriptional Regulator Blimp-1 by Dark Zone Germinal Center B Cells During Periods of Proliferation.
Radtke D. and Bannard O., (2018), Front Immunol, 9
Germinal centers: programmed for affinity maturation and antibody diversification.
Bannard O. and Cyster JG., (2017), Curr Opin Immunol, 45, 21 - 30
Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses.
Bannard O. et al, (2016), J Exp Med, 213, 993 - 1009
Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells.
Rodda LB. et al, (2015), J Immunol, 195, 4781 - 4791
Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1.
Dos Santos LI. et al, (2015), Cancer Immunol Immunother, 64, 311 - 323
Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness.
Wang X. et al, (2014), J Immunol, 192, 4601 - 4609
Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection.
Bannard O. et al, (2013), Immunity, 39, 912 - 924
MIR-17 similar to 92 promotes T follicular helper cell differentiation and represses subset-inappropriate gene expression
Baumjohann D. et al, (2013), CYTOKINE, 63, 246 - 247
The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression.
Baumjohann D. et al, (2013), Nat Immunol, 14, 840 - 848
CXCR4 promotes B cell egress from Peyer's patches.
Schmidt TH. et al, (2013), J Exp Med, 210, 1099 - 1107
Immunology. When less signaling is more.
Bannard OM. and Cyster JG., (2012), Science, 336, 1120 - 1121
Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection.
Mackay LK. et al, (2012), J Immunol, 188, 2173 - 2178
Cutting edge: Virus-specific CD8+ T cell clones and the maintenance of replicative function during a persistent viral infection.
Bannard O. et al, (2010), J Immunol, 185, 7141 - 7145
Pathways of memory CD8+ T-cell development.
Bannard O. et al, (2009), Eur J Immunol, 39, 2083 - 2087