Recent publications published by researchers at the MRC WIMM.
Germinal centers output clonally diverse plasma cell populations expressing high- and low-affinity antibodies.
Journal article
Sprumont A. et al, (2023), Cell
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center.
Journal article
Grootveld AK. et al, (2023), Cell, 186, 1144 - 1161.e18
Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites.
Journal article
MacLean AJ. et al, (2022), Immunity, 55, 718 - 733.e8
Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection.
Journal article
Frost JN. et al, (2021), Med, 2, 164 - 179.e12
Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging.
Journal article
Stewart I. et al, (2018), Immunity, 49, 477 - 489.e7
Expression of the Plasma Cell Transcriptional Regulator Blimp-1 by Dark Zone Germinal Center B Cells During Periods of Proliferation.
Journal article
Radtke D. and Bannard O., (2018), Front Immunol, 9
Germinal centers: programmed for affinity maturation and antibody diversification.
Journal article
Bannard O. and Cyster JG., (2017), Curr Opin Immunol, 45, 21 - 30
Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses.
Journal article
Bannard O. et al, (2016), J Exp Med, 213, 993 - 1009
Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells.
Journal article
Rodda LB. et al, (2015), J Immunol, 195, 4781 - 4791
Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1.
Journal article
Dos Santos LI. et al, (2015), Cancer Immunol Immunother, 64, 311 - 323
Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness.
Journal article
Wang X. et al, (2014), J Immunol, 192, 4601 - 4609
Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection.
Journal article
Bannard O. et al, (2013), Immunity, 39, 912 - 924
The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression.
Journal article
Baumjohann D. et al, (2013), Nat Immunol, 14, 840 - 848
CXCR4 promotes B cell egress from Peyer's patches.
Journal article
Schmidt TH. et al, (2013), J Exp Med, 210, 1099 - 1107
MIR-17 ∼ 92 promotes T follicular helper cell differentiation and represses subset-inappropriate gene expression
Conference paper
Baumjohann D. et al, (2013), CYTOKINE, 63, 246 - 247
Immunology. When less signaling is more.
Journal article
Bannard OM. and Cyster JG., (2012), Science, 336, 1120 - 1121
Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection.
Journal article
Mackay LK. et al, (2012), J Immunol, 188, 2173 - 2178
Cutting edge: Virus-specific CD8+ T cell clones and the maintenance of replicative function during a persistent viral infection.
Journal article
Bannard O. et al, (2010), J Immunol, 185, 7141 - 7145
Pathways of memory CD8+ T-cell development.
Journal article
Bannard O. et al, (2009), Eur J Immunol, 39, 2083 - 2087