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Recent publications published by researchers at the MRC WIMM.

Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.

Journal article

Hulikova A. et al, (2022), Basic Res Cardiol, 117

Defining genome architecture at base-pair resolution.

Journal article

Hua P. et al, (2021), Nature, 595, 125 - 129

BET inhibition disrupts transcription but retains enhancer-promoter contact.

Journal article

Crump NT. et al, (2021), Nat Commun, 12

Why are so many MLL lysine methyltransferases required for normal mammalian development?

Journal article

Crump NT. and Milne TA., (2019), Cell Mol Life Sci, 76, 2885 - 2898

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Journal article

Godfrey L. et al, (2019), Nat Commun, 10

Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition.

Journal article

Dancy BM. et al, (2012), Chembiochem, 13, 2113 - 2121

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP.

Journal article

Crump NT. et al, (2011), Proc Natl Acad Sci U S A, 108, 7814 - 7819

Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome.

Journal article

Worrall JAR. et al, (2008), J Mol Biol, 382, 870 - 883

Stress-activated MAP kinases in chromatin and transcriptional complexes

Journal article

Crump NT. et al, (2008), Topics in Current Genetics, 20, 283 - 297