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Recent publications published by the researchers at the MRC WIMM.

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors.

Journal article

Booth CAG. et al, (2018), Cancer Cell, 33, 274 - 291.e8

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Journal article

Pasricha S-R. et al, (2017), Nat Commun, 8

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.

Journal article

Liao C. et al, (2017), Neurology, 88, 131 - 142

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers

Journal article

Hsia LT. et al, (2016), Proceedings of the National Academy of Sciences of the United States of America, 113, E2162 - E2171

Separation of cancer cells from white blood cells by pinched flow fractionation.

Journal article

Pødenphant M. et al, (2015), Lab Chip, 15, 4598 - 4606

Relationship between genome and epigenome--challenges and requirements for future research.

Journal article

Almouzni G. et al, (2014), BMC Genomics, 15

Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors.

Journal article

Ashley N. et al, (2013), Cancer Res, 73, 5798 - 5809

Regulation of intestinal cancer stem cells.

Journal article

Ashley N., (2013), Cancer Lett, 338, 120 - 126

Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling.

Journal article

Ashley N. and Poulton J., (2009), Oncogene, 28, 3880 - 3891

Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs.

Journal article

Ashley N. and Poulton J., (2009), Biochem Biophys Res Commun, 378, 450 - 455

Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances.

Journal article

Ashley N. et al, (2007), Hum Mol Genet, 16, 1400 - 1411

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