Recent publications published by researchers at the MRC WIMM.
Pharmacological targeting of BMAL1 modulates circadian and immune pathways.
Pu H. et al, (2025), Nat Chem Biol
Shift work and evening chronotype are associated with hepatic fat fraction and non-alcoholic fatty liver disease in 282,303 UK biobank participants.
Maidstone R. et al, (2023), Endocr Connect
CATCH-UP: A High-Throughput Upstream-Pipeline for Bulk ATAC-Seq and ChIP-Seq Data.
Riva SG. et al, (2023), J Vis Exp
The interplay between macronutrients and sleep: focus on circadian and homeostatic processes.
Gangitano E. et al, (2023), Front Nutr, 10
Circadian clock function does not require the histone methyltransferase MLL3.
Baxter M. et al, (2022), FASEB J, 36
Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism.
Downton P. et al, (2022), Proc Natl Acad Sci U S A, 119
Circadian rhythms in innate immunity and stress responses.
Baxter M. and Ray DW., (2020), Immunology, 161, 261 - 267
Hypoxia regulates GR function through multiple mechanisms involving microRNAs 103 and 107.
Yang N. et al, (2020), Mol Cell Endocrinol, 518
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.
Kitchen GB. et al, (2020), Proc Natl Acad Sci U S A, 117, 1543 - 1551
Cardiac mitochondrial function depends on BUD23 mediated ribosome programming.
Baxter M. et al, (2020), Elife, 9
An improved method for quantitative ChIP studies of nuclear receptor function.
Hunter AL. et al, (2019), J Mol Endocrinol, 62, 169 - 177
Genome-wide effect of pulmonary airway epithelial cell-specific Bmal1 deletion.
Zhang Z. et al, (2019), FASEB J, 33, 6226 - 6238
REVERBa couples the circadian clock to hepatic glucocorticoid action.
Caratti G. et al, (2018), J Clin Invest, 128, 4454 - 4471
Glucocorticoid receptor function in health and disease.
Caratti G. et al, (2015), Clin Endocrinol (Oxf), 83, 441 - 448
Role of transient receptor potential and pannexin channels in cigarette smoke-triggered ATP release in the lung.
Baxter M. et al, (2014), Thorax, 69, 1080 - 1089
Transient receptor potential (TRP) channels in the airway: role in airway disease.
Grace MS. et al, (2014), British journal of pharmacology, 171, 2593 - 2607